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LOC127820657 OCT4-NANOG hESC enhancer GRCh37_chr11:25600863-25601516 [ Homo sapiens (human) ]

Gene ID: 127820657, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127820657
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr11:25600863-25601516
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127820657 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (25579317..25579970)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (25718734..25719387)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (25600863..25601516)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene leucine zipper protein 2 Neighboring gene NANOG hESC enhancer GRCh37_chr11:24659075-24659576 Neighboring gene NANOG hESC enhancer GRCh37_chr11:24701323-24702247 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:24718961-24720160 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:24768484-24769683 Neighboring gene NANOG hESC enhancer GRCh37_chr11:24777043-24777544 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:25060809-25060990 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:25115650-25116150 Neighboring gene N-acetylneuraminic acid phosphatase pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr11:25509719-25510220 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:25523381-25523976 Neighboring gene long intergenic non-protein coding RNA 2699 Neighboring gene V-type proton ATPase subunit G 1-like Neighboring gene ribosomal protein L36a pseudogene 40

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_122116.1 

    Range
    101..754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    25579317..25579970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    25718734..25719387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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