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LOC127823074 H3K4me1 hESC enhancer GRCh37_chr11:130030913-130031412 [ Homo sapiens (human) ]

Gene ID: 127823074, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127823074
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:130030913-130031412
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127823074 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (130161018..130161517)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (130196687..130197186)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (130030913..130031412)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor like protein 2 Neighboring gene ribosomal protein L34 pseudogene 21 Neighboring gene MPRA-validated peak1513 silencer Neighboring gene uncharacterized LOC124902850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:129993119-129993620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:129993621-129994120 Neighboring gene Sharpr-MPRA regulatory region 10235 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:130015754-130016953 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4078 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4079 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5752 Neighboring gene ST14 transmembrane serine protease matriptase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:130068001-130068502 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:130079505-130080004 Neighboring gene zinc finger and BTB domain containing 44 Neighboring gene NDUFAF2 pseudogene 2 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:130165506-130166038 Neighboring gene DEAD-box helicase 18 pseudogene 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_124513.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    130161018..130161517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    130196687..130197186
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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