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LOC127825158 NANOG hESC enhancer GRCh37_chr12:114222326-114222862 [ Homo sapiens (human) ]

Gene ID: 127825158, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127825158
Gene description
NANOG hESC enhancer GRCh37_chr12:114222326-114222862
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127825158 in Genome Data Viewer
Location:
chromosome: 12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (113784521..113785057)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (113760358..113760894)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (114222326..114222862)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369991 Neighboring gene VISTA enhancer hs1571 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114132877-114133376 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114140827-114141326 Neighboring gene long intergenic non-protein coding RNA 1234 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114206803-114207314 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_24661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114215183-114215682 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114243165-114243665 Neighboring gene dynein light chain LC8-type 1 pseudogene 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114255753-114256680 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114256681-114257606 Neighboring gene RNA binding motif protein 19 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114294867-114295368 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:114295369-114295868 Neighboring gene uncharacterized LOC124903025 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr12:114300792-114301991

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_126671.1 

    Range
    101..637
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    113784521..113785057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    113760358..113760894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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