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LOC127825229 H3K4me1 hESC enhancer GRCh37_chr12:117010377-117010877 [ Homo sapiens (human) ]

Gene ID: 127825229, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127825229
Gene description
H3K4me1 hESC enhancer GRCh37_chr12:117010377-117010877
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127825229 in Genome Data Viewer
Location:
chromosome: 12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (116572572..116573072)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (116553768..116554268)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (117010377..117010877)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:116956174-116956674 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:116956675-116957175 Neighboring gene long intergenic non-protein coding RNA 2457 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr12:116965601-116966800 Neighboring gene ReSE screen-validated silencer GRCh37_chr12:116971051-116971252 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:116972615-116973149 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7093 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:116977845-116978345 Neighboring gene long intergenic non-protein coding RNA 173 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:116996681-116997190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7095 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7096 Neighboring gene Sharpr-MPRA regulatory region 12411 Neighboring gene microtubule associated protein 1 light chain 3 beta 2 Neighboring gene Sharpr-MPRA regulatory region 4921 Neighboring gene uncharacterized LOC124903028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:117096334-117096837 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:117100573-117101197 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:117103598-117104149 Neighboring gene long intergenic non-protein coding RNA 3088 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7097 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7098 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7099 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:117154997-117155526 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr12:117155527-117156056 Neighboring gene SREBF pathway regulator in golgi 1 Neighboring gene NANOG hESC enhancer GRCh37_chr12:117164433-117164934 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr12:117174416-117175374 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4904 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4905

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_126742.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    116572572..116573072
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    116553768..116554268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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