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LOC127826553 H3K27ac hESC enhancer GRCh37_chr13:79980055-79981046 [ Homo sapiens (human) ]

Gene ID: 127826553, updated on 12-Sep-2024

Summary

Gene symbol
LOC127826553
Gene description
H3K27ac hESC enhancer GRCh37_chr13:79980055-79981046
Gene type
biological region
Feature type(s)
regulatory: enhancer, silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region includes an enhancer that was validated by the ChIP-STARR-seq massively parallel reporter assay (MPRA) in primed human embryonic stem cells, where it is marked by the H3K27ac histone modification. This locus also includes two accessible chromatin subregions, one of which was validated as an enhancer and the other as a silencer based on their ability to activate or repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) MPRA in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

See LOC127826553 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (79405811..79406911)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (78633880..78634980)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (79979946..79981046)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5425 Neighboring gene BCAS2 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7850 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7851 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7852 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:79772046-79772677 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7853 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7854 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7855 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:79853422-79854140 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:79857373-79858352 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr13:79862351-79862939 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:79881601-79882102 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:79904806-79905306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:79905307-79905807 Neighboring gene RNA binding motif protein 26 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7856 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7857 Neighboring gene RNA, 5S ribosomal pseudogene 33 Neighboring gene RBM26 antisense RNA 1 Neighboring gene uncharacterized LOC105370274 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5427 Neighboring gene NDFIP2 antisense RNA 1 Neighboring gene Nedd4 family interacting protein 2

Genomic regions, transcripts, and products

General gene information

Other Names

  • ATAC-STARR-seq lymphoblastoid active region 7858
  • ATAC-STARR-seq lymphoblastoid silent region 5426

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128060.2 

    Range
    101..1201
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    79405811..79406911
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    78633880..78634980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)