U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127826784 OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:101162162-101162780 [ Homo sapiens (human) ]

Gene ID: 127826784, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127826784
Gene description
OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:101162162-101162780
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC127826784 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (100509908..100510526)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (99725170..99725788)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (101162162..101162780)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene propionyl-CoA carboxylase subunit alpha Neighboring gene uncharacterized LOC107984574 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:101144770-101145270 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:101145271-101145771 Neighboring gene PCCA antisense RNA 1 Neighboring gene RPL7L1 pseudogene 6 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:101154747-101155384 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:101161543-101162161 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:101162781-101163398 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101169316-101170040 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101171491-101172156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101177366-101177888 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101182623-101183592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101196750-101197473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:101197474-101198196 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:101198945-101199623 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:101199624-101200301 Neighboring gene ribosomal protein S26 pseudogene 47 Neighboring gene gamma-glutamylamine cyclotransferase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5477 Neighboring gene transmembrane O-mannosyltransferase targeting cadherins 4 Neighboring gene cytochrome c oxidase subunit 5B pseudogene 6

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128289.1 

    Range
    101..719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    100509908..100510526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    99725170..99725788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases