U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LOC127829623 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59664350-59664853 [ Homo sapiens (human) ]

Gene ID: 127829623, updated on 12-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
LOC127829623
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59664350-59664853
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See LOC127829623 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (59372151..59372654)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (57174246..57174749)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (59664350..59664853)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene myosin IE Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:59521359-59521858 Neighboring gene RNA, U4 small nuclear 80, pseudogene Neighboring gene Sharpr-MPRA regulatory region 2447 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6487 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:59596416-59596592 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9487 Neighboring gene NANOG hESC enhancer GRCh37_chr15:59620781-59621282 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9488 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59645915-59646434 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59646435-59646955 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59646956-59647475 Neighboring gene RNA, U6 small nuclear 212, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:59652703-59653204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:59653205-59653704 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59657838-59658422 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59658423-59659005 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6488 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:59664854-59665358 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:59672263-59672764 Neighboring gene uncharacterized LOC124903597 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9489 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9490 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9491 Neighboring gene Sharpr-MPRA regulatory region 1182 Neighboring gene family with sequence similarity 81 member A Neighboring gene NSA2 pseudogene 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131105.1 

    Range
    101..604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    59372151..59372654
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    57174246..57174749
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases