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LOC127829809 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65655395-65656260 [ Homo sapiens (human) ]

Gene ID: 127829809, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127829809
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65655395-65656260
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (65363057..65363922)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (63172432..63173297)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (65655395..65656260)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:65588516-65589427 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65593529-65594044 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6555 Neighboring gene RNA, U5A small nuclear 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9595 Neighboring gene RNA, U5B small nuclear 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65618173-65618716 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65624736-65625408 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65626438-65627016 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65627017-65627595 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65628175-65628752 Neighboring gene immunoglobulin superfamily DCC subclass member 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65647365-65647867 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65647868-65648370 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65648371-65648873 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65659717-65660580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65660581-65661444 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:65677106-65677717 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9598 Neighboring gene immunoglobulin superfamily DCC subclass member 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65702937-65703594 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65707062-65707929 Neighboring gene uncharacterized LOC124903510 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:65710136-65710346 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9599 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9600 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:65715563-65716097 Neighboring gene dipeptidyl peptidase 8 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:65809274-65809827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9601

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131291.1 

    Range
    101..966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    65363057..65363922
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    63172432..63173297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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