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LOC127830609 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89910855-89911468 [ Homo sapiens (human) ]

Gene ID: 127830609, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127830609
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89910855-89911468
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127830609 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (89367624..89368237)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (87123681..87124294)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10047 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10048 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10049 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:89880071-89880240 Neighboring gene tRNA-Arg (anticodon TCG) 1-1 Neighboring gene POLG divergent transcript Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr15:89891730-89892929 Neighboring gene uncharacterized LOC124903549 Neighboring gene Sharpr-MPRA regulatory region 10069 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6794 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6795 Neighboring gene MIR9-3 host gene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:89913278-89914160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:89914161-89915042 Neighboring gene microRNA 9-3 Neighboring gene uncharacterized LOC107984777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10051 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89943355-89943880 Neighboring gene uncharacterized LOC105371031 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89943881-89944405 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10052 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr15:89950909-89951506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89959457-89959966 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89959967-89960475

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_132089.1 

    Range
    101..714
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    89367624..89368237
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    87123681..87124294
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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