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LOC127830645 H3K27ac hESC enhancer GRCh37_chr15:90634376-90634876 [ Homo sapiens (human) ]

Gene ID: 127830645, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127830645
Gene description
H3K27ac hESC enhancer GRCh37_chr15:90634376-90634876
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127830645 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (90091144..90091644)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (87847169..87847669)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (90634376..90634876)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 710 Neighboring gene microRNA 3174 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90581285-90581804 Neighboring gene Sharpr-MPRA regulatory region 12348 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90585951-90586930 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90597371-90598254 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90602135-90602846 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10061 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10062 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6809 Neighboring gene ZNF710 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90627210-90627710 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90627711-90628211 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90630317-90631230 Neighboring gene NANOG hESC enhancer GRCh37_chr15:90638658-90639182 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90644126-90644981 Neighboring gene isocitrate dehydrogenase (NADP(+)) 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90644982-90645836 Neighboring gene IDH2 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90664819-90665318 Neighboring gene Sharpr-MPRA regulatory region 4454 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90686773-90687307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10063 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90701094-90701611 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90701612-90702128 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90704142-90704734 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:90704735-90705327 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:90707039-90707194 Neighboring gene RNA, 7SL, cytoplasmic 346, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_132125.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    90091144..90091644
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    87847169..87847669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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