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LOC127830669 NANOG-H3K27ac hESC enhancer GRCh37_chr15:90955563-90956294 [ Homo sapiens (human) ]

Gene ID: 127830669, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127830669
Gene description
NANOG-H3K27ac hESC enhancer GRCh37_chr15:90955563-90956294
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (90412331..90413062)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (88168346..88169077)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12979 Neighboring gene zinc finger protein 774 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6819 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90938261-90938762 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:90938763-90939262 Neighboring gene NADH:ubiquinone oxidoreductase subunit A3 pseudogene 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6820 Neighboring gene IQ motif containing GTPase activating protein 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr15:90957593-90958792 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10077 Neighboring gene MPRA-validated peak2420 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr15:90999383-90999894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10078 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:91054233-91054732 Neighboring gene MPRA-validated peak2421 silencer Neighboring gene MPRA-validated peak2422 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6821 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6822 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6823 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10079 Neighboring gene CREB regulated transcription coactivator 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:91106113-91106613 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6824 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:91126557-91127068 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr15:91127069-91127580 Neighboring gene uncharacterized LOC124903555 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:91137296-91137796 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10080 Neighboring gene Sharpr-MPRA regulatory region 4613 Neighboring gene uncharacterized LOC124903554

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_132149.1 

    Range
    101..832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    90412331..90413062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    88168346..88169077
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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