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LOC127883118 NANOG hESC enhancer GRCh37_chr16:10050616-10051155 [ Homo sapiens (human) ]

Gene ID: 127883118, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127883118
Gene description
NANOG hESC enhancer GRCh37_chr16:10050616-10051155
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127883118 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (9956759..9957298)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (9990775..9991314)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (10050616..10051155)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 404 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:9764099-9764878 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:9767805-9768370 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:9768371-9768936 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:9770634-9771198 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:9771199-9771764 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:9773923-9774850 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:9774851-9775778 Neighboring gene uncharacterized LOC105371077 Neighboring gene glutamate ionotropic receptor NMDA type subunit 2A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10376 Neighboring gene uncharacterized LOC105371076 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:10132543-10133043 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7188 Neighboring gene Sharpr-MPRA regulatory region 8841 Neighboring gene inosine monophosphate dehydrogenase 1 pseudogene 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_133084.1 

    Range
    101..640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    9956759..9957298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    9990775..9991314
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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