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LOC127883372 H3K27ac hESC enhancer GRCh37_chr16:19894183-19894913 [ Homo sapiens (human) ]

Gene ID: 127883372, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127883372
Gene description
H3K27ac hESC enhancer GRCh37_chr16:19894183-19894913
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127883372 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (19882861..19883591)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (19813631..19814361)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (19894183..19894913)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene IQ motif containing K Neighboring gene uncharacterized LOC105371115 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:19778410-19778910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:19778911-19779411 Neighboring gene LARP7 pseudogene 2 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19864519-19865437 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19865438-19866357 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:19869508-19870707 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19871981-19872562 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19873143-19873723 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19879518-19880020 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:19883504-19884004 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19887125-19887940 Neighboring gene G protein-coupled receptor class C group 5 member B Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19890529-19891258 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19891259-19891990 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:19891991-19892720 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:19892721-19893452 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:19893453-19894182 Neighboring gene Sharpr-MPRA regulatory region 8054 Neighboring gene uncharacterized LOC105371116 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr16:19980466-19980966 Neighboring gene uncharacterized LOC105371117 Neighboring gene uncharacterized LOC124903660

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_133338.1 

    Range
    101..831
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    19882861..19883591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    19813631..19814361
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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