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LOC127884140 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57918039-57918586 [ Homo sapiens (human) ]

Gene ID: 127884140, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127884140
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57918039-57918586
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127884140 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (57884135..57884682)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (63679372..63679919)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene kinesin family member C3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10915 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10916 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57850615-57851160 Neighboring gene uncharacterized LOC388282 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:57858755-57859256 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:57859257-57859756 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:57869467-57869968 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:57869969-57870468 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57871284-57872020 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57879667-57880550 Neighboring gene RNA, U6 small nuclear 20, pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57880551-57881432 Neighboring gene NANOG hESC enhancer GRCh37_chr16:57907038-57907565 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10917 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57917491-57918038 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7538 Neighboring gene cyclic nucleotide gated channel subunit beta 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:57945302-57946008 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57972707-57973534 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57973535-57974362 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:57998489-57998988 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10918 Neighboring gene sperm microtubule inner protein 8 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10919 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7539 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7540 Neighboring gene zinc finger protein 319 Neighboring gene U6 snRNA biogenesis phosphodiesterase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_139665.1 

    Range
    101..648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    57884135..57884682
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    63679372..63679919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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