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LOC127884402 H3K27ac hESC enhancer GRCh37_chr16:69788499-69789121 [ Homo sapiens (human) ]

Gene ID: 127884402, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127884402
Gene description
H3K27ac hESC enhancer GRCh37_chr16:69788499-69789121
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127884402 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (69754596..69755218)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (75557130..75557752)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (69788499..69789121)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr16:69753551-69753732 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:69760025-69761224 Neighboring gene NAD(P)H quinone dehydrogenase 1 Neighboring gene NQO1 divergent transcript Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:69787875-69788498 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:69796040-69796618 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7667 Neighboring gene NIN1 (RPN12) binding protein 1 homolog Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11045 Neighboring gene non-POU domain containing, octamer-binding pseudogene 1 Neighboring gene WW domain containing E3 ubiquitin protein ligase 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11046 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11047 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:69924551-69925074 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr16:69950984-69952183 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:69964206-69964363 Neighboring gene microRNA 140

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_134182.1 

    Range
    101..723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    69754596..69755218
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    75557130..75557752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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