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LOC127885732 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8955351-8956008 [ Homo sapiens (human) ]

Gene ID: 127885732, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127885732
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8955351-8956008
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127885732 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (9052034..9052691)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (8959225..8959882)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (8955351..8956008)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903921 Neighboring gene phosphoinositide-3-kinase regulatory subunit 5 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8189 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11717 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11718 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8857999-8858500 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8858501-8859000 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8191 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8192 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11719 Neighboring gene PIK3R5 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11720 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11721 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8193 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8194 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8907139-8907768 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11722 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8195 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8924225-8924768 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8936035-8936534 Neighboring gene netrin 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr17:8954033-8954690 and GRCh37_chr17:8954691-8955350 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8956741-8957362 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8957363-8957982 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:8957983-8958603 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8990973-8991474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:8991475-8991974 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9041579-9042287 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:9054043-9054886 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9058975-9059476 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9059477-9059976 Neighboring gene uncharacterized LOC101928266 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9083413-9083914 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9086141-9086640 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9099203-9100124 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr17:9124521-9125720 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:9128413-9128964 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:9129517-9130068 Neighboring gene uncharacterized LOC124903923 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9130069-9130619 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9131120-9131620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:9133199-9133700

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_135467.1 

    Range
    101..758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    9052034..9052691
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    8959225..8959882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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