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LOC127886521 NANOG hESC enhancer GRCh37_chr17:31740081-31740603 [ Homo sapiens (human) ]

Gene ID: 127886521, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127886521
Gene description
NANOG hESC enhancer GRCh37_chr17:31740081-31740603
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127886521 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (33413063..33413585)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (34359120..34359642)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (31740081..31740603)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371737 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:31439262-31440461 Neighboring gene acid sensing ion channel subunit 2 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr17:31519773-31520284 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr17:31520285-31520795 Neighboring gene uncharacterized LOC124903985 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:31588469-31588970 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:31588971-31589470 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:31619340-31619510 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr17:31689385-31689886 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr17:31689887-31690386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:31707898-31708398 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:31708399-31708899 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr17:31779502-31780247 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12040 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:31795840-31796340 Neighboring gene uncharacterized LOC112268206 Neighboring gene uncharacterized LOC100506677

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_136234.1 

    Range
    101..623
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    33413063..33413585
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    34359120..34359642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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