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LOC127889413 NANOG hESC enhancer GRCh37_chr18:55523486-55524043 [ Homo sapiens (human) ]

Gene ID: 127889413, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127889413
Gene description
NANOG hESC enhancer GRCh37_chr18:55523486-55524043
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127889413 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (57856254..57856811)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (58056476..58057033)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (55523486..55524043)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 8B1 Neighboring gene uncharacterized LOC124904310 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr18:55443057-55444256 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:55470167-55470804 Neighboring gene Sharpr-MPRA regulatory region 4888 Neighboring gene MPRA-validated peak3165 silencer Neighboring gene Sharpr-MPRA regulatory region 13131 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13378 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13379 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13380 Neighboring gene ribosomal L24 domain containing 1 pseudogene 11 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:55561711-55562212 Neighboring gene uncharacterized LOC105372140 Neighboring gene MPRA-validated peak3167 silencer Neighboring gene long intergenic non-protein coding RNA 1897

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_138945.1 

    Range
    101..658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    57856254..57856811
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    58056476..58057033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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