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LOC127890832 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18256091-18256592 [ Homo sapiens (human) ]

Gene ID: 127890832, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127890832
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18256091-18256592
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127890832 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (18145281..18145782)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (18279383..18279883)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (18256091..18256592)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12288 Neighboring gene interleukin 12 receptor subunit beta 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14295 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14296 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10368 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10369 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10370 Neighboring gene microtubule associated serine/threonine kinase 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18220925-18221494 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18228711-18229582 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:18232970-18234169 Neighboring gene uncharacterized LOC124904650 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18256593-18257093 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14300 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18263346-18264238 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10374 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18267436-18268294 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:18270202-18270406 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:18271190-18271739 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10375 Neighboring gene phosphoinositide-3-kinase regulatory subunit 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14302 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14303 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10376 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14304 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:18285185-18285850 Neighboring gene IFI30 lysosomal thiol reductase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_140740.1 

    Range
    101..602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    18145281..18145782
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    18279383..18279883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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