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LOC127892308 H3K27ac hESC enhancer GRCh37_chr19:57814007-57814506 [ Homo sapiens (human) ]

Gene ID: 127892308, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127892308
Gene description
H3K27ac hESC enhancer GRCh37_chr19:57814007-57814506
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127892308 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (57302639..57303138)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (60399145..60399644)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (57814007..57814506)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15128 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11073 Neighboring gene Sharpr-MPRA regulatory region 2652 Neighboring gene zinc finger protein 805 Neighboring gene NANOG hESC enhancer GRCh37_chr19:57774577-57775110 Neighboring gene ZNF460 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11074 Neighboring gene Sharpr-MPRA regulatory region 5355 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:57791112-57792311 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11075 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15130 Neighboring gene zinc finger protein 460 Neighboring gene PPPDE peptidase domain containing 1 pseudogene Neighboring gene Sharpr-MPRA regulatory region 10022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:57830216-57830733 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15131 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15132 Neighboring gene zinc finger protein 543

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_142121.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    57302639..57303138
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    60399145..60399644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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