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LOC127892561 OCT4 hESC enhancer GRCh37_chr20:6617898-6618411 [ Homo sapiens (human) ]

Gene ID: 127892561, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127892561
Gene description
OCT4 hESC enhancer GRCh37_chr20:6617898-6618411
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 transcription factor. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127892561 in Genome Data Viewer
Location:
chromosome: 20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (6637251..6637764)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (6678424..6678937)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (6617898..6618411)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904866 Neighboring gene cancer susceptibility 20 Neighboring gene Sharpr-MPRA regulatory region 6239 Neighboring gene MPRA-validated peak4139 silencer Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:6571340-6572539 Neighboring gene Sharpr-MPRA regulatory region 6314 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr20:6593736-6594935 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:6678222-6679421 Neighboring gene Sharpr-MPRA regulatory region 10991 Neighboring gene long intergenic non-protein coding RNA 1713 Neighboring gene BMP2 5' regulatory region Neighboring gene uncharacterized LOC105372517

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_142361.1 

    Range
    101..614
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    6637251..6637764
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    6678424..6678937
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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