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LOC127893610 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48185591-48186205 [ Homo sapiens (human) ]

Gene ID: 127893610, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127893610
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48185591-48186205
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127893610 in Genome Data Viewer
Location:
chromosome: 20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (49569054..49569668)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (51338644..51339258)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (48185591..48186205)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372649 Neighboring gene NANOG hESC enhancer GRCh37_chr20:47985158-47985711 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:47990213-47990475 Neighboring gene potassium voltage-gated channel subfamily B member 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48040793-48041316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48041317-48041840 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48063137-48063648 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48063649-48064158 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48064159-48064670 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12997 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12998 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48121719-48122220 Neighboring gene prostaglandin I2 synthase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18062 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:48158843-48159119 Neighboring gene uncharacterized LOC101927486 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48184974-48185590 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48196657-48197231 Neighboring gene uncharacterized LOC105372651 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48212298-48212798 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:48227493-48227993 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13000 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18063 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18064 Neighboring gene uncharacterized LOC124904926 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18066 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:48247798-48248480

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_143332.1 

    Range
    101..715
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    49569054..49569668
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    51338644..51339258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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