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LOC127894117 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60953065-60953666 [ Homo sapiens (human) ]

Gene ID: 127894117, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894117
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60953065-60953666
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894117 in Genome Data Viewer
Location:
chromosome: 20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (62378009..62378610)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (64173555..64174156)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (60953065..60953666)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 5 Neighboring gene uncharacterized LOC124904946 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18197 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60929780-60930720 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60930721-60931659 Neighboring gene LAMA5 antisense RNA 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60935576-60936276 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60936277-60936975 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60936976-60937675 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60937676-60938374 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18198 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60939075-60939774 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60939775-60940474 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60941173-60941872 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13109 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60943971-60944670 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:60946071-60946768 Neighboring gene uncharacterized LOC105372708 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:60949451-60950054 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60950055-60950656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:60956340-60957020 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18199 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18200 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:60961625-60962316 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:60962317-60963008 Neighboring gene RPS21 divergent transcript Neighboring gene ribosomal protein S21

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_143813.1 

    Range
    101..702
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    62378009..62378610
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    64173555..64174156
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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