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LOC127894224 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61879175-61880007 [ Homo sapiens (human) ]

Gene ID: 127894224, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894224
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61879175-61880007
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894224 in Genome Data Viewer
Location:
chromosome: 20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (63247823..63248655)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (65053837..65054669)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (61879175..61880007)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61830673-61831272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61831273-61831874 Neighboring gene YTH N6-methyladenosine RNA binding protein F1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13148 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13149 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61857740-61858694 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61862252-61863021 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:61863095-61864294 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:61865058-61865253 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61866073-61866674 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18225 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61870596-61871096 Neighboring gene uncharacterized LOC124904950 Neighboring gene baculoviral IAP repeat containing 7 Neighboring gene microRNA 3196 Neighboring gene sodium/potassium transporting ATPase interacting 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61880008-61880839 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61883491-61883999 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61885071-61885602 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61885603-61886134 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61889508-61890125 Neighboring gene uncharacterized LOC100192386 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:61891361-61891976 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13150 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13151 Neighboring gene ARF GTPase activating protein 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:61915538-61916038 Neighboring gene microRNA 4326

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_143913.1 

    Range
    101..933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    63247823..63248655
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    65053837..65054669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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