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LOC127894507 H3K4me1 hESC enhancer GRCh37_chr21:32554821-32555320 [ Homo sapiens (human) ]

Gene ID: 127894507, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894507
Gene description
H3K4me1 hESC enhancer GRCh37_chr21:32554821-32555320
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894507 in Genome Data Viewer
Location:
chromosome: 21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (31182504..31183003)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (29550224..29550723)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (32554821..32555320)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_61959 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18351 Neighboring gene keratin associated protein 19-8 Neighboring gene ubiquitin protein ligase E3A pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18352 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18353 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr21:32530991-32531520 Neighboring gene TIAM Rac1 associated GEF 1 Neighboring gene Sharpr-MPRA regulatory region 15669 Neighboring gene uncharacterized LOC105372777 Neighboring gene MPRA-validated peak4402 silencer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr21:32710674-32711873 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:32738744-32739943 Neighboring gene MPRA-validated peak4404 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr21:32822900-32823113 Neighboring gene MTRES1 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_144161.1 

    Range
    101..600
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    31182504..31183003
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    29550224..29550723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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