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LOC127894617 H3K4me1 hESC enhancer GRCh37_chr21:37978989-37979489 [ Homo sapiens (human) ]

Gene ID: 127894617, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127894617
Gene description
H3K4me1 hESC enhancer GRCh37_chr21:37978989-37979489
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127894617 in Genome Data Viewer
Location:
chromosome: 21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (36606691..36607191)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (34988842..34989342)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (37978989..37979489)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene ATP synthase membrane subunit f pseudogene 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:37780832-37782031 Neighboring gene chromatin assembly factor 1 subunit B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:37802462-37803337 Neighboring gene CLDN14 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18434 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:37836794-37837391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37842779-37843278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18435 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18436 Neighboring gene claudin 14 Neighboring gene proteasome 26S subunit, non-ATPase 4 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18437 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18438 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18439 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13288 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18440 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37973046-37973546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37973547-37974047 Neighboring gene uncharacterized LOC105369308 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38031419-38031920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38031921-38032420 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr21:38067894-38068806 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38072642-38073235 Neighboring gene uncharacterized LOC107985492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38073236-38073828 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38077313-38078142 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38078973-38079802 Neighboring gene SIM bHLH transcription factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_144264.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    36606691..36607191
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    34988842..34989342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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