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LOC127896602 NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44554289-44554822 [ Homo sapiens (human) ]

Gene ID: 127896602, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127896602
Gene description
NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44554289-44554822
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127896602 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (44158409..44158942)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (44641569..44642102)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905131 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13861 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13862 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13863 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19197 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19200 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19201 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19199 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19198 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19202 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19203 Neighboring gene parvin beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44433869-44434401 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44441960-44442509 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44444424-44445372 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:44447510-44448390 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44451418-44451918 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44459805-44460304 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44463139-44463704 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44463705-44464268 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19205 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19206 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44464833-44465396 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:44501635-44502135 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr22:44502229-44503124 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44503125-44504019 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44504020-44504914 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44541321-44541950 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44541951-44542580 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44543839-44544468 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44550653-44551476 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44551477-44552300 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44553755-44554288 Neighboring gene tRNA-SeC (anticodon TCA) 2-1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:44556425-44556958 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44563307-44564086 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44565977-44566498 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19207 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19208 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44570650-44571382 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13864 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44576792-44577522 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44577523-44578252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44578253-44578982 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13866 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44588052-44588637 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44588638-44589222 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44596327-44597136 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44597948-44598757 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44600018-44600518 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44600519-44601019 Neighboring gene parvin gamma Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44616903-44617455 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44658947-44659462 Neighboring gene shisa like 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44676595-44677095 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44678007-44678506 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:44685764-44686707 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44688595-44689536 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44694997-44695529 Neighboring gene uncharacterized LOC101927499

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146119.1 

    Range
    101..634
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    44158409..44158942
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    44641569..44642102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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