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LOC127896864 H3K4me1 hESC enhancer GRCh37_chr22:48209585-48210084 [ Homo sapiens (human) ]

Gene ID: 127896864, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127896864
Gene description
H3K4me1 hESC enhancer GRCh37_chr22:48209585-48210084
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127896864 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (47813836..47814335)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (48306326..48306825)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (48209585..48210084)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1644 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:47945374-47946198 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:47954815-47955315 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:47965246-47965746 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr22:47983860-47985059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48021971-48022470 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48024594-48025473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48025474-48026352 Neighboring gene long intergenic non-protein coding RNA 898 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:48055109-48055612 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:48055613-48056116 Neighboring gene Sharpr-MPRA regulatory region 4711 Neighboring gene epigenetically induced MYC interacting lncRNA 1 Neighboring gene NANOG hESC enhancer GRCh37_chr22:48123351-48123882 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48135325-48135934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48171821-48172322 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48172323-48172822 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:48260220-48260392 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr22:48268308-48269507 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr22:48279628-48280827 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:48363686-48363861 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48438360-48438860 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:48438861-48439361 Neighboring gene uncharacterized LOC124905150 Neighboring gene MPRA-validated peak4509 silencer Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:48479499-48480083 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:48480084-48480668 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19273 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19274 Neighboring gene uncharacterized LOC107985536

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146367.1 

    Range
    101..600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    47813836..47814335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    48306326..48306825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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