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LOC127898350 OCT4-NANOG hESC enhancer GRCh37_chrX:132783454-132784145 [ Homo sapiens (human) ]

Gene ID: 127898350, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127898350
Gene description
OCT4-NANOG hESC enhancer GRCh37_chrX:132783454-132784145
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127898350 in Genome Data Viewer
Location:
chromosome: X
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (133649426..133650117)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (131974557..131975248)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (132783454..132784145)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:132439404-132439904 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:132440918-132441832 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:132446467-132446966 Neighboring gene NANOG hESC enhancer GRCh37_chrX:132484838-132485339 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:132501328-132501828 Neighboring gene glypican 4 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:132549756-132550256 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:132551379-132551918 Neighboring gene NANOG hESC enhancer GRCh37_chrX:132568407-132568958 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:132571583-132572295 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:132689082-132689878 Neighboring gene RNA, U6 small nuclear 203, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chrX:132712962-132713463 Neighboring gene glypican 3 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:132808889-132809502 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:132819803-132820460 Neighboring gene ribosomal protein S24 pseudogene 19 Neighboring gene ribosomal protein SA pseudogene 63

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_147666.1 

    Range
    101..792
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    133649426..133650117
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    131974557..131975248
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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