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SNHG11 small nucleolar RNA host gene 11 [ Homo sapiens (human) ]

Gene ID: 128439, updated on 17-Mar-2024

Summary

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Official Symbol
SNHG11provided by HGNC
Official Full Name
small nucleolar RNA host gene 11provided by HGNC
Primary source
HGNC:HGNC:25046
See related
Ensembl:ENSG00000174365 MIM:619494; AllianceGenome:HGNC:25046
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf198; LINC00101; NCRNA00101
Summary
This gene is a member of the non-protein-coding multiple snoRNA host gene family. Two snoRNAs are derived from the introns of this host gene. Although many alternative splice variants have been observed, the gene is thought to have no protein-coding potential. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in testis (RPKM 6.8), prostate (RPKM 5.3) and 25 other tissues See more
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Genomic context

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Location:
20q11.23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (38446654..38450921)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (40174250..40178518)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (37075297..37079564)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904958 Neighboring gene small nucleolar RNA host gene 17 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17857 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17858 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene small nucleolar RNA, H/ACA box 71D Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17859 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:37076132-37076686 Neighboring gene small nucleolar RNA, H/ACA box 71E Neighboring gene small nucleolar RNA, H/ACA box 60 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12899 Neighboring gene Ral GTPase activating protein non-catalytic subunit beta Neighboring gene microRNA 548o-2 Neighboring gene ribosomal protein S3 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways. Deng Y, et al. Pathol Res Pract, 2022 Jun. PMID 35487027
  2. LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis. Huang W, et al. Anticancer Drugs, 2022 Jul 1. PMID 35324517
  3. Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer. Li Y, et al. Horm Metab Res, 2022 Mar. PMID 35276744
  4. Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis. Fang X, et al. Cell Biol Int, 2022 Jan. PMID 34519129
  5. Dexmedetomidine improves oxygen-glucose deprivation/reoxygenation (OGD/R) -induced neurological injury through regulating SNHG11/miR-324-3p/VEGFA axis. Chen Y, et al. Bioengineered, 2021 Dec. PMID 34334080, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. [LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway].
    Title: [LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway].
  2. SNHG11: A New Budding Star in Tumors and Inflammatory Diseases.
    Title: SNHG11: A New Budding Star in Tumors and Inflammatory Diseases.
  3. The function of long non-coding RNA SNHG11 and its working mechanism in triple-negative breast cancer.
    Title: The function of long non-coding RNA SNHG11 and its working mechanism in triple-negative breast cancer.
  4. Long non-coding RNA SNHG11 regulates the Wnt/beta-catenin signaling pathway through rho/ROCK in trabecular meshwork cells.
    Title: Long non-coding RNA SNHG11 regulates the Wnt/β-catenin signaling pathway through rho/ROCK in trabecular meshwork cells.
  5. lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.
    Title: lncRNA SNHG11 promotes the development of colorectal cancer by mediating miR-339-3p/SHOX2.
  6. LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways.
    Title: LncRNA SNHG11 accelerates the progression of lung adenocarcinoma via activating Notch pathways.
  7. LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis.
    Title: LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis.
  8. Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer.
    Title: Prognostic Value of Long Noncoding RNA SNHG11 in Patients with Prostate Cancer.
  9. Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis.
    Title: Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis.
  10. lncRNA SNHG11 facilitates prostate cancer progression through the upregulation of IGF1R expression and by sponging miR184.
    Title: lncRNA SNHG11 facilitates prostate cancer progression through the upregulation of IGF‑1R expression and by sponging miR‑184.
Submit: New GeneRIF Correction See all GeneRIFs (19)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • long intergenic non-protein coding RNA 101
  • small nucleolar RNA host gene (non-protein coding) 11
  • small nucleolar RNA host gene 11 (non-protein coding)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003239.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AF454939, AF497716, AK055434
    Related
    ENST00000656815.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    38446654..38450921
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    40174250..40178518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_139016.2: Suppressed sequence

    Description
    NM_139016.2: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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