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SLX4IP SLX4 interacting protein [ Homo sapiens (human) ]

Gene ID: 128710, updated on 17-Sep-2024

Summary

Official Symbol
SLX4IPprovided by HGNC
Official Full Name
SLX4 interacting proteinprovided by HGNC
Primary source
HGNC:HGNC:16225
See related
Ensembl:ENSG00000149346 MIM:615958; AllianceGenome:HGNC:16225
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C20orf94; bA204H22.1; bA254M13.1; dJ1099D15.3
Expression
Ubiquitous expression in skin (RPKM 1.0), testis (RPKM 0.9) and 25 other tissues See more
Orthologs
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Genomic context

See SLX4IP in Genome Data Viewer
Location:
20p12.2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (10435305..10628030)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (10478114..10671152)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (10415953..10608678)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene SDA1 domain containing 1 pseudogene 2 Neighboring gene uncharacterized LOC128706665 Neighboring gene uncharacterized LOC128706666 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:10399946-10401145 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12671 Neighboring gene NANOG hESC enhancer GRCh37_chr20:10412265-10412766 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17543 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17544 Neighboring gene MKKS centrosomal shuttling protein Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr20:10447220-10447919 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17545 Neighboring gene Sharpr-MPRA regulatory region 2397 Neighboring gene Sharpr-MPRA regulatory region 8388 Neighboring gene Sharpr-MPRA regulatory region 5326 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:10529678-10530178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17547 Neighboring gene Sharpr-MPRA regulatory region 6934 Neighboring gene Sharpr-MPRA regulatory region 11569 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:10578661-10579860 Neighboring gene DNAJC9 pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10617378-10618174 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10618175-10618971 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10621299-10622074 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10622075-10622850 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12672 Neighboring gene Sharpr-MPRA regulatory region 15707 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12673 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12674 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12675 Neighboring gene microRNA 6870 Neighboring gene jagged canonical Notch ligand 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:10686119-10687318 Neighboring gene long intergenic non-protein coding RNA 1752

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr interacts with TSPYL1 and C20orf94 subunits of the SLX4 complex in Vpr-expressing THP-1 cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009608.3NP_001009608.1  protein SLX4IP

    See identical proteins and their annotated locations for NP_001009608.1

    Status: VALIDATED

    Source sequence(s)
    AL035456, BC026094, CA416447
    Consensus CDS
    CCDS33439.1
    UniProtKB/Swiss-Prot
    Q05CG2, Q05CT9, Q5VYV7
    Related
    ENSP00000335557.5, ENST00000334534.10
    Conserved Domains (1) summary
    pfam15744
    Location:10366
    UPF0492; Uncharacterized protein family UPF0492

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    10435305..10628030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    10478114..10671152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054322966.1XP_054178941.1  protein SLX4IP isoform X1

  2. XM_054322967.1XP_054178942.1  protein SLX4IP isoform X2