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LOC129663329 ReSE screen-validated silencer GRCh37_chr13:31312711-31312902 [ Homo sapiens (human) ]

Gene ID: 129663329, updated on 12-Sep-2024

Summary

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Gene symbol
LOC129663329
Gene description
ReSE screen-validated silencer GRCh37_chr13:31312711-31312902
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in phorbol 12-myristate 13-acetate-treated (for megakaryocytic differentiation) K562 erythroleukemia cells. [provided by RefSeq, Apr 2023]
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Genomic context

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See LOC129663329 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (30738574..30738765)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (29960675..29960866)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (31312711..31312902)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7540 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7542 Neighboring gene ubiquitin specific peptidase like 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31233439-31234198 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5236 Neighboring gene tRNA-Asn (anticodon GTT) 2-4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7544 Neighboring gene MPRA-validated peak2063 silencer Neighboring gene uncharacterized LOC124903146 Neighboring gene arachidonate 5-lipoxygenase activating protein Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr13:31317812-31319011 Neighboring gene VISTA enhancer hs1515 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr13:31372741-31373940 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:31379396-31379896 Neighboring gene long intergenic non-protein coding RNA 398 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:31398576-31399105 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:31401421-31402065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7545 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7546 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31436564-31437514 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31437515-31438463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:31445187-31445996 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:31445997-31446806 Neighboring gene long intergenic non-protein coding RNA 545 Neighboring gene TEX26 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic identification of silencers in human cells. Pang B, et al. Nat Genet, 2020 Mar. PMID 32094911, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_160335.1 

    Range
    101..292
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    30738574..30738765
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    29960675..29960866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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