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LOC129663394 ReSE screen-validated silencer GRCh37_chr13:114456174-114456392 [ Homo sapiens (human) ]

Gene ID: 129663394, updated on 12-Sep-2024

Summary

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Gene symbol
LOC129663394
Gene description
ReSE screen-validated silencer GRCh37_chr13:114456174-114456392
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region used in a lentiviral ReSE (repressive ability of silencer elements) screen that assays for cell survival based on transcriptional repression of an apoptosis-inducing fusion protein. This region was identified as a functional silencer in K562 erythroleukemia cells. [provided by RefSeq, Apr 2023]
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Genomic context

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See LOC129663394 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (113753201..113753419)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (112962156..112962374)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (114456174..114456392)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114305936-114306560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114306561-114307185 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114311832-114312332 Neighboring gene ATPase H+/K+ transporting subunit beta Neighboring gene G protein-coupled receptor kinase 1 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:114426222-114426826 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114426827-114427432 Neighboring gene basic salivary proline-rich protein 4-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114446225-114446726 Neighboring gene long intergenic non-protein coding RNA 552 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114461359-114461860 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114462417-114462918 Neighboring gene transmembrane protein 255B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:114491163-114491692 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:114491693-114492221 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:114504133-114505007 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114506713-114507271 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8040 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8041 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8042 Neighboring gene uncharacterized LOC124903220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:114523566-114524115 Neighboring gene GAS6 antisense RNA 1 Neighboring gene growth arrest specific 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Systematic identification of silencers in human cells. Pang B, et al. Nat Genet, 2020 Mar. PMID 32094911, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_160400.1 

    Range
    101..319
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    113753201..113753419
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_021160011.1 Reference GRCh38.p14 PATCHES

    Range
    54800..55018
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187596.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    26691..26909
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    112962156..112962374
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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