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LOC129933044 ATAC-STARR-seq lymphoblastoid active region 15273 [ Homo sapiens (human) ]

Gene ID: 129933044, updated on 12-Sep-2024

Summary

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Gene symbol
LOC129933044
Gene description
ATAC-STARR-seq lymphoblastoid active region 15273
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC129933044 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (8682246..8682295)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (8705969..8706018)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (8822376..8822425)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373411 Neighboring gene SNRPE pseudogene 5 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:8773308-8774507 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8777331-8777854 Neighboring gene VISTA enhancer hs1527 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:8802380-8803579 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8815873-8816791 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8816792-8817709 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:8818423-8818956 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8818957-8819490 Neighboring gene NANOG hESC enhancer GRCh37_chr2:8821385-8821888 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8824708-8825498 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:8825499-8826288 Neighboring gene ID2 antisense RNA 1 Neighboring gene inhibitor of DNA binding 2 Neighboring gene kinase D interacting substrate 220 Neighboring gene ARF like GTPase 1 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15274 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11129 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11130 Neighboring gene Sharpr-MPRA regulatory region 5743 Neighboring gene NANOG hESC enhancer GRCh37_chr2:8995048-8995599 Neighboring gene membrane bound O-acyltransferase domain containing 2 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_166069.1 

    Range
    101..150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    8682246..8682295
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    8705969..8706018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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