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LOC130006570 ATAC-STARR-seq lymphoblastoid active region 5380 [ Homo sapiens (human) ]

Gene ID: 130006570, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130006570
Gene description
ATAC-STARR-seq lymphoblastoid active region 5380
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130006570 in Genome Data Viewer
Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (88303404..88303463)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (88222423..88222482)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (88036572..88036631)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984361 Neighboring gene NANOG hESC enhancer GRCh37_chr11:87550635-87551136 Neighboring gene MT-CYB pseudogene 41 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:87636982-87638181 Neighboring gene RAB38, member RAS oncogene family Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:87678230-87678751 Neighboring gene NANOG hESC enhancer GRCh37_chr11:87681659-87682160 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5376 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5377 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5378 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:87957258-87957458 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:87979456-87980655 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5379 Neighboring gene microRNA 3166 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:88030550-88031243 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:88040649-88041604 Neighboring gene MPRA-validated peak1386 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5381 Neighboring gene Sharpr-MPRA regulatory region 1780 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5382 Neighboring gene uncharacterized LOC101929174 Neighboring gene CRISPRi-validated cis-regulatory element chr11.4755 Neighboring gene CRISPRi-validated cis-regulatory element chr11.4758 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5383 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5384 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5385 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5386 Neighboring gene cathepsin C Neighboring gene glyceraldehyde 3 phosphate dehydrogenase pseudogene 70 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3833 Neighboring gene GRM5 antisense RNA 1 Neighboring gene glutamate metabotropic receptor 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_186015.1 

    Range
    101..160
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    88303404..88303463
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    88222423..88222482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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