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LOC130057879 ATAC-STARR-seq lymphoblastoid silent region 6795 [ Homo sapiens (human) ]

Gene ID: 130057879, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130057879
Gene description
ATAC-STARR-seq lymphoblastoid silent region 6795
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130057879 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (89359230..89359279)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (87115286..87115335)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (89902461..89902510)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10047 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10048 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10049 Neighboring gene tRNA-Arg (anticodon TCG) 1-1 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:89880071-89880240 Neighboring gene POLG divergent transcript Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr15:89891730-89892929 Neighboring gene uncharacterized LOC124903549 Neighboring gene Sharpr-MPRA regulatory region 10069 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6794 Neighboring gene MIR9-3 host gene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:89910855-89911468 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:89913278-89914160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:89914161-89915042 Neighboring gene microRNA 9-3 Neighboring gene uncharacterized LOC107984777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10051

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_192300.1 

    Range
    101..150
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    89359230..89359279
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    87115286..87115335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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