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pigb-1 Mannosyltransferase [ Caenorhabditis elegans ]

Gene ID: 13184808, updated on 2-Nov-2024

Summary

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Official Symbol
pigb-1
Official Full Name
Mannosyltransferase
Primary source
WormBase:WBGene00194986
Locus tag
CELE_T27F7.4
See related
AllianceGenome:WB:WBGene00194986
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 80. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pigb-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003280.10 (4991587..4993077, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene SUI1 domain-containing protein Neighboring gene Charged multivesicular body protein 3 Neighboring gene Ribonuclease H1;Ribonuclease H1 N-terminal domain-containing protein Neighboring gene Conserved secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables alpha-1,2-mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mannosyltransferase
NP_001254097.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    4991587..4993077 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267168.1 → NP_001254097.1  Mannosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254097.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EDN2
    Conserved Domains (1) summary
    cl21590
    Location:1 → 425
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase
Nucleotide Protein
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Gene LinkOut

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