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LOC132443843 STARR-positive B cell enhancer ABC_E4149 [ Mus musculus (house mouse) ]

Gene ID: 132443843, updated on 10-Feb-2024

Summary

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Gene symbol
LOC132443843
Gene description
STARR-positive B cell enhancer ABC_E4149
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
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Genomic context

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See LOC132443843 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (100320844..100321145)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene methyltransferase hypoxia inducible domain containing 1 Neighboring gene thiol methyltransferase 1A2 Neighboring gene HIG1 domain family, member 1C Neighboring gene predicted gene, 53911 Neighboring gene solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Neighboring gene predicted gene 5475 Neighboring gene RIKEN cDNA 5330439K02 gene Neighboring gene STARR-positive B cell enhancer mm9_chr15:100274003-100274304 Neighboring gene STARR-seq mESC enhancer starr_39750 Neighboring gene STARR-seq mESC enhancer starr_39751 Neighboring gene LETM1 domain containing 1 Neighboring gene cysteine-serine-rich nuclear protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_240265.1 

    Range
    101..402
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    100320844..100321145
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version