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LOC132445292 STARR-positive B cell enhancer ABC_E7683 [ Mus musculus (house mouse) ]

Gene ID: 132445292, updated on 10-Feb-2024

Summary

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Gene symbol
LOC132445292
Gene description
STARR-positive B cell enhancer ABC_E7683
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This genomic region was identified as a putative B cell regulatory element by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing). It was validated as an enhancer by standard reporter assays in CH12 B lymphoma cells, and also by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
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Genomic context

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See LOC132445292 in Genome Data Viewer
Location:
chromosome: 19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (61214370..61214765)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6020 Neighboring gene mortality factor 4 like 2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10002 Neighboring gene M-phase specific PLK1 intereacting protein like 1 Neighboring gene STARR-positive B cell enhancer mm9_chr19:61257593-61257894 Neighboring gene STARR-positive B cell enhancer ABC_E5715 Neighboring gene STARR-positive B cell enhancer ABC_E7682 Neighboring gene STARR-positive B cell enhancer ABC_E9054 Neighboring gene colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Neighboring gene STARR-positive B cell enhancer ABC_E2533 Neighboring gene predicted gene 4242 Neighboring gene DCP1 decapping enzyme homolog A pseudogene Neighboring gene glycine cleavage system protein H (aminomethyl carrier) pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene regulatory networks STARR-ing B cells. Martínez de Paz A, et al. Nat Immunol, 2020 Feb. PMID 31873293, Free PMC Article
  2. Charting the cis-regulome of activated B cells by coupling structural and functional genomics. Chaudhri VK, et al. Nat Immunol, 2020 Feb. PMID 31873292

GeneRIFs: Gene References Into Functions

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_241710.2 

    Range
    101..496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    61214370..61214765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version