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Epb41l3 erythrocyte membrane protein band 4.1 like 3 [ Mus musculus (house mouse) ]

Gene ID: 13823, updated on 28-Oct-2024

Summary

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Official Symbol
Epb41l3provided by MGI
Official Full Name
erythrocyte membrane protein band 4.1 like 3provided by MGI
Primary source
MGI:MGI:103008
See related
Ensembl:ENSMUSG00000024044 AllianceGenome:MGI:103008
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4.1B; Dal1; NBL3; DAL1P; Epb4.1l3
Summary
Predicted to enable cytoskeletal protein-membrane anchor activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including nervous system development; paranodal junction maintenance; and protein localization to axon. Located in juxtaparanode region of axon; paranode region of axon; and postsynaptic density. Colocalizes with axolemma. Is expressed in several structures, including central nervous system; notochord; paraxial mesenchyme; and retina. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma. Orthologous to human EPB41L3 (erythrocyte membrane protein band 4.1 like 3). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Broad expression in cerebellum adult (RPKM 14.3), frontal lobe adult (RPKM 11.1) and 15 other tissues See more
Orthologs
human all
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Genomic context

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See Epb41l3 in Genome Data Viewer
Location:
17 E1.3; 17 40.15 cM
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (69382642..69596986)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (69075647..69289991)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36392 Neighboring gene STARR-seq mESC enhancer starr_43113 Neighboring gene STARR-seq mESC enhancer starr_43114 Neighboring gene STARR-seq mESC enhancer starr_43115 Neighboring gene predicted gene, 36437 Neighboring gene STARR-seq mESC enhancer starr_43116 Neighboring gene VISTA enhancer mm1658 Neighboring gene STARR-seq mESC enhancer starr_43119 Neighboring gene RIKEN cDNA 2410021H03 gene Neighboring gene STARR-seq mESC enhancer starr_43121 Neighboring gene STARR-seq mESC enhancer starr_43123 Neighboring gene STARR-seq mESC enhancer starr_43125 Neighboring gene predicted gene, 53973 Neighboring gene zinc finger and BTB domain containing 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular and functional characterization of protein 4.1B, a novel member of the protein 4.1 family with high level, focal expression in brain. Parra M, et al. J Biol Chem, 2000 Feb 4. PMID 10652311
  2. Protein 4.1B in mouse islets of Langerhans and beta-cell tumorigenesis. Terada N, et al. Histochem Cell Biol, 2003 Oct. PMID 14574582
  3. Immunohistochemical study of protein 4.1B in the normal and W/W(v) mouse seminiferous epithelium. Terada N, et al. J Histochem Cytochem, 2004 Jun. PMID 15150285
  4. A 130-kDa protein 4.1B regulates cell adhesion, spreading, and migration of mouse embryo fibroblasts by influencing actin cytoskeleton organization. Wang J, et al. J Biol Chem, 2014 Feb 28. PMID 24381168, Free PMC Article
  5. Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells. Wang C, et al. Int J Med Sci, 2019. PMID 31171904, Free PMC Article

See all (77) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. our data indicate that 4.1B is an important regulator during EMT progression in melanoma cells, which may present a potential target for the prevention and treatment of melanoma.
    Title: Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells.
  2. This paper herein showed the immunolocalization and interaction proteins of MPP6 in the mouse small intestine, and also that 4.1B in epithelial cells was not essential for the sorting of MPP6.
    Title: Immunohistochemical study of the membrane skeletal protein, membrane protein palmitoylated 6 (MPP6), in the mouse small intestine.
  3. findings document novel, isoform-selective roles for 130-kDa 4.1B in adhesion, spreading, and migration of MEF cells by affecting actin organization
    Title: A 130-kDa protein 4.1B regulates cell adhesion, spreading, and migration of mouse embryo fibroblasts by influencing actin cytoskeleton organization.
  4. The results of this study demonstrated that 4.1B is a key cytoskeletal scaffold for axonal adhesion molecules expressed in the juxtaparanodal and internodal domains that unexpectedly regulates myelin sheath thickness.
    Title: The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.
  5. in myelinated axons 4.1B contributes to the stabilization of membrane proteins at paranodes, to the clustering of juxtaparanodal proteins, and to the regulation of the internodal axon caliber.
    Title: Protein 4.1B contributes to the organization of peripheral myelinated axons.
  6. Protein 4.1B plays a key role in ensuring the proper molecular compartmentalization of hemi-node-type region of axons of motor neurons.
    Title: Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B.
  7. 4.1B plays a pivotal role in interactions between the paranodal AGSJs and axonal cytoskeleton.
    Title: The cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons.
  8. 4.1B was specifically and constantly expressed in the stereocilia tips during postnatal development.
    Title: Protein 4.1 expression in the developing hair cells of the mouse inner ear.
  9. In this study, the expression of 4.1B and its interaction with tumor suppressor in lung cancer-1 were examined in rodent adrenal gland, and the involvement of 4.1B in tumorigenesis
    Title: Dispensable role of protein 4.1B/DAL-1 in rodent adrenal medulla regarding generation of pheochromocytoma and plasmalemmal localization of TSLC1.
  10. We propose that the 4.1B-containing membrane skeleton may play a role in regulating the Na(+) and HCO(3)(-) reabsorption in S1-S2 proximal tubules.
    Title: Interaction of membrane skeletal protein, protein 4.1B and p55, and sodium bicarbonate cotransporter1 in mouse renal S1-S2 proximal tubules.
Submit: New GeneRIF Correction See all GeneRIFs (15)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (6)  1 citation

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal protein-membrane anchor activity TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in axon development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cortical cytoskeleton organization TAS
Traceable Author Statement
more info
 PubMed 
involved_in myelin maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in neuron projection morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in paranodal junction assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in paranodal junction maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to juxtaparanode region of axon IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to paranode region of axon IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with axolemma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
  
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
  
located_in cell-cell junction ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in juxtaparanode region of axon IDA
Inferred from Direct Assay
more info
 PubMed 
located_in paranode region of axon IDA
Inferred from Direct Assay
more info
 PubMed 
located_in paranode region of axon ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
band 4.1-like protein 3
Names
DAL-1
differentially expressed in adenocarcinoma of the lung protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355732.1 → NP_001342661.1  band 4.1-like protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC151281, AC154761, BC079858
    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:421 → 467
    SAB; SAB domain
    pfam05902
    Location:681 → 786
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 330
    FA; FERM adjacent (FA)
    cl26557
    Location:507 → 641
    RNase_E_G; Ribonuclease E/G family

  2. NM_001355733.1 → NP_001342662.1  band 4.1-like protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC151281, BC079858
    Consensus CDS
    CCDS89142.1
    UniProtKB/TrEMBL
    B6ZHD1, D0VYV6
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:540 → 586
    SAB; SAB domain
    pfam05902
    Location:798 → 903
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  3. NM_001355734.1 → NP_001342663.1  band 4.1-like protein 3 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC151281, BC079858
    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:732 → 778
    SAB; SAB domain
    pfam05902
    Location:992 → 1097
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)
    cl25865
    Location:4 → 82
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  4. NM_001355735.1 → NP_001342664.1  band 4.1-like protein 3 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC151281, BC079858
    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:714 → 760
    SAB; SAB domain
    pfam05902
    Location:974 → 1079
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)
    cl25865
    Location:4 → 82
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  5. NM_001355736.1 → NP_001342665.1  band 4.1-like protein 3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC151281, BC079858
    Consensus CDS
    CCDS28952.1
    UniProtKB/Swiss-Prot
    Q69ZT8, Q9R102, Q9WV92
    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:556 → 602
    SAB; SAB domain
    pfam05902
    Location:816 → 921
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)
    cl25865
    Location:4 → 82
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

  6. NM_001424759.1 → NP_001411688.1  band 4.1-like protein 3 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC151281
    Related
    ENSMUSP00000153611.2, ENSMUST00000223703.2

  7. NM_001424760.1 → NP_001411689.1  band 4.1-like protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC151281
    UniProtKB/TrEMBL
    D0VYV6
    Related
    ENSMUSP00000156566.2, ENSMUST00000233509.2

  8. NM_013813.2 → NP_038841.1  band 4.1-like protein 3 isoform 1

    See identical proteins and their annotated locations for NP_038841.1

    Status: VALIDATED

    Source sequence(s)
    AF152247, BC079858
    Consensus CDS
    CCDS28952.1
    UniProtKB/Swiss-Prot
    Q69ZT8, Q9R102, Q9WV92
    UniProtKB/TrEMBL
    B6ZHD1
    Related
    ENSMUSP00000079098.6, ENSMUST00000080208.7
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:556 → 602
    SAB; SAB domain
    pfam05902
    Location:816 → 921
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)
    cl25865
    Location:4 → 82
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    69382642..69596986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249482.1 → XP_030105342.1  band 4.1-like protein 3 isoform X16

    UniProtKB/TrEMBL
    A0A286YDY4
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK14949
    Location:566 → 863
    PRK14949; DNA polymerase III subunits gamma and tau; Provisional
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:617 → 663
    SAB; SAB domain
    pfam05902
    Location:875 → 980
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 330
    FA; FERM adjacent (FA)

  2. XM_017317239.2 → XP_017172728.1  band 4.1-like protein 3 isoform X37

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:525 → 659
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:441 → 487
    SAB; SAB domain
    pfam05902
    Location:699 → 804
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 330
    FA; FERM adjacent (FA)

  3. XM_036160309.1 → XP_036016202.1  band 4.1-like protein 3 isoform X38

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:525 → 659
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:439 → 487
    SAB; SAB domain
    pfam05902
    Location:699 → 777
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 332
    FA; FERM adjacent (FA)

  4. XM_036160313.1 → XP_036016206.1  band 4.1-like protein 3 isoform X42

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:491 → 618
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:439 → 487
    SAB; SAB domain
    pfam05902
    Location:658 → 736
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 332
    FA; FERM adjacent (FA)

  5. XM_036160308.1 → XP_036016201.1  band 4.1-like protein 3 isoform X36

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:529 → 663
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:443 → 491
    SAB; SAB domain
    pfam05902
    Location:703 → 808
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 332
    FA; FERM adjacent (FA)

  6. XM_036160311.1 → XP_036016204.1  band 4.1-like protein 3 isoform X39

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:507 → 641
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:421 → 469
    SAB; SAB domain
    pfam05902
    Location:681 → 759
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 332
    FA; FERM adjacent (FA)

  7. XM_036160312.1 → XP_036016205.1  band 4.1-like protein 3 isoform X41

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:3 → 192
    B41; Band 4.1 homologues
    PRK10811
    Location:473 → 600
    rne; ribonuclease E; Reviewed
    cd13184
    Location:187 → 280
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:421 → 469
    SAB; SAB domain
    pfam05902
    Location:640 → 745
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:289 → 332
    FA; FERM adjacent (FA)

  8. XM_030249487.2 → XP_030105347.1  band 4.1-like protein 3 isoform X25

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:558 → 604
    SAB; SAB domain
    pfam05902
    Location:816 → 894
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  9. XM_030249488.2 → XP_030105348.1  band 4.1-like protein 3 isoform X26

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:608 → 735
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:558 → 604
    SAB; SAB domain
    pfam05902
    Location:775 → 880
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  10. XM_030249472.1 → XP_030105332.1  band 4.1-like protein 3 isoform X2

    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:737 → 784
    SAB; SAB domain
    pfam05902
    Location:1294 → 1399
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  11. XM_036160302.1 → XP_036016195.1  band 4.1-like protein 3 isoform X13

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:766 → 893
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:714 → 762
    SAB; SAB domain
    pfam05902
    Location:933 → 1011
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  12. XM_006523612.4 → XP_006523675.1  band 4.1-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006523675.1

    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:755 → 802
    SAB; SAB domain
    pfam05902
    Location:1312 → 1417
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  13. XM_030249489.1 → XP_030105349.1  band 4.1-like protein 3 isoform X27

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:630 → 764
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:804 → 882
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  14. XM_030249492.1 → XP_030105352.1  band 4.1-like protein 3 isoform X33

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:596 → 723
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:763 → 841
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  15. XM_030249491.1 → XP_030105351.1  band 4.1-like protein 3 isoform X32

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:612 → 739
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:561 → 608
    SAB; SAB domain
    pfam05902
    Location:779 → 857
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  16. XM_030249490.1 → XP_030105350.1  band 4.1-like protein 3 isoform X29

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:540 → 586
    SAB; SAB domain
    pfam05902
    Location:798 → 876
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  17. XM_036160306.1 → XP_036016199.1  band 4.1-like protein 3 isoform X31

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:578 → 705
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:527 → 574
    SAB; SAB domain
    pfam05902
    Location:745 → 850
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  18. XM_030249494.1 → XP_030105354.1  band 4.1-like protein 3 isoform X35

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Related
    ENSMUSP00000156827.2, ENSMUST00000233964.2
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:578 → 705
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:527 → 574
    SAB; SAB domain
    pfam05902
    Location:745 → 823
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  19. XM_030249495.1 → XP_030105355.1  band 4.1-like protein 3 isoform X40

    UniProtKB/TrEMBL
    D0VYV7
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:499 → 641
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:681 → 759
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  20. XM_006523613.4 → XP_006523676.1  band 4.1-like protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006523676.1

    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:755 → 802
    SAB; SAB domain
    pfam05902
    Location:1312 → 1417
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  21. XM_017317238.2 → XP_017172727.1  band 4.1-like protein 3 isoform X28

    UniProtKB/TrEMBL
    A0A3B2WBE1, A7YY80
    Related
    ENSMUSP00000153228.2, ENSMUST00000225977.2
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:596 → 723
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:763 → 868
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  22. XM_017317227.3 → XP_017172716.1  band 4.1-like protein 3 isoform X2

    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:737 → 784
    SAB; SAB domain
    pfam05902
    Location:1294 → 1399
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  23. XM_011246283.1 → XP_011244585.1  band 4.1-like protein 3 isoform X5

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:806 → 933
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:755 → 802
    SAB; SAB domain
    pfam05902
    Location:973 → 1078
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  24. XM_030249478.1 → XP_030105338.1  band 4.1-like protein 3 isoform X8

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:806 → 933
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:755 → 802
    SAB; SAB domain
    pfam05902
    Location:973 → 1051
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  25. XM_030249477.1 → XP_030105337.1  band 4.1-like protein 3 isoform X6

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:734 → 780
    SAB; SAB domain
    pfam05902
    Location:992 → 1070
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  26. XM_036160299.1 → XP_036016192.1  band 4.1-like protein 3 isoform X7

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:784 → 911
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:732 → 780
    SAB; SAB domain
    pfam05902
    Location:951 → 1056
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  27. XM_030249475.1 → XP_030105335.1  band 4.1-like protein 3 isoform X3

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:721 → 768
    SAB; SAB domain
    pfam05902
    Location:1005 → 1110
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  28. XM_030249476.1 → XP_030105336.1  band 4.1-like protein 3 isoform X4

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:721 → 768
    SAB; SAB domain
    pfam05902
    Location:980 → 1085
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  29. XM_011246285.1 → XP_011244587.1  band 4.1-like protein 3 isoform X11

    UniProtKB/TrEMBL
    D0VYV7
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:697 → 835
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:875 → 980
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  30. XM_030249480.1 → XP_030105340.1  band 4.1-like protein 3 isoform X12

    UniProtKB/TrEMBL
    B6ZHD1
    Related
    ENSMUSP00000108300.2, ENSMUST00000112680.8
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:579 → 626
    SAB; SAB domain
    pfam05902
    Location:838 → 943
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  31. XM_036160305.1 → XP_036016198.1  band 4.1-like protein 3 isoform X22

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:608 → 735
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:556 → 604
    SAB; SAB domain
    pfam05902
    Location:775 → 853
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  32. XM_017317231.1 → XP_017172720.1  band 4.1-like protein 3 isoform X14

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:829 → 934
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  33. XM_017317232.1 → XP_017172721.1  band 4.1-like protein 3 isoform X18

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:829 → 907
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  34. XM_030249483.1 → XP_030105343.1  band 4.1-like protein 3 isoform X17

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:545 → 592
    SAB; SAB domain
    pfam05902
    Location:804 → 909
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  35. XM_011246290.1 → XP_011244592.1  band 4.1-like protein 3 isoform X30

    UniProtKB/TrEMBL
    A0A3B2WD96, D0VYV7
    Related
    ENSMUSP00000156921.2, ENSMUST00000232706.2
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:517 → 659
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:699 → 804
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  36. XM_036160307.1 → XP_036016200.1  band 4.1-like protein 3 isoform X34

    UniProtKB/TrEMBL
    D0VYV7
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:517 → 659
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam05902
    Location:699 → 777
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  37. XM_036160300.1 → XP_036016193.1  band 4.1-like protein 3 isoform X9

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:766 → 893
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:714 → 762
    SAB; SAB domain
    pfam05902
    Location:933 → 1038
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  38. XM_030249481.1 → XP_030105341.1  band 4.1-like protein 3 isoform X15

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:540 → 586
    SAB; SAB domain
    pfam05902
    Location:823 → 928
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  39. XM_036160304.1 → XP_036016197.1  band 4.1-like protein 3 isoform X21

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:590 → 717
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:538 → 586
    SAB; SAB domain
    pfam05902
    Location:757 → 862
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 449
    FA; FERM adjacent (FA)

  40. XM_030249486.1 → XP_030105346.1  band 4.1-like protein 3 isoform X24

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:590 → 717
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:540 → 586
    SAB; SAB domain
    pfam05902
    Location:757 → 835
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  41. XM_030249484.1 → XP_030105344.1  band 4.1-like protein 3 isoform X20

    UniProtKB/TrEMBL
    A0A3B2WBE1
    Conserved Domains (6) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    PRK10811
    Location:637 → 771
    rne; ribonuclease E; Reviewed
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:527 → 574
    SAB; SAB domain
    pfam05902
    Location:811 → 889
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)

  42. XM_017317234.1 → XP_017172723.1  band 4.1-like protein 3 isoform X19

    UniProtKB/TrEMBL
    B6ZHD1
    Conserved Domains (5) summary
    smart00295
    Location:120 → 309
    B41; Band 4.1 homologues
    cd13184
    Location:304 → 397
    FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
    pfam04382
    Location:527 → 574
    SAB; SAB domain
    pfam05902
    Location:786 → 891
    4_1_CTD; 4.1 protein C-terminal domain (CTD)
    pfam08736
    Location:406 → 447
    FA; FERM adjacent (FA)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9WV92.1 GenPept UniProtKB/Swiss-Prot:Q9WV92

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