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RBFOX3 RNA binding fox-1 homolog 3 [ Homo sapiens (human) ]

Gene ID: 146713, updated on 3-Apr-2024

Summary

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Official Symbol
RBFOX3provided by HGNC
Official Full Name
RNA binding fox-1 homolog 3provided by HGNC
Primary source
HGNC:HGNC:27097
See related
Ensembl:ENSG00000167281 MIM:616999; AllianceGenome:HGNC:27097
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FOX3; NEUN; FOX-3; HRNBP3
Summary
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
Expression
Biased expression in brain (RPKM 11.3), prostate (RPKM 4.9) and 4 other tissues See more
Orthologs
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Genomic context

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See RBFOX3 in Genome Data Viewer
Location:
17q25.3
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (79089345..79665571, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (79984286..80563418, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (77085427..77632826, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9078 Neighboring gene C1QTNF1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77040047-77040547 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:77042736-77043935 Neighboring gene Sharpr-MPRA regulatory region 5335 Neighboring gene C1q and TNF related 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9079 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77094193-77094906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77099175-77100160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77112846-77113750 Neighboring gene endo-beta-N-acetylglucosaminidase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77157651-77158151 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77173286-77173965 Neighboring gene uncharacterized LOC124904069 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77179359-77180239 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9080 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77188893-77189550 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77198565-77199383 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77207229-77207739 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77219238-77219738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77219739-77220239 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77223705-77224476 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12916 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77362366-77362866 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:77369816-77369979 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:77397348-77397522 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77400039-77400540 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77403781-77404282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77404283-77404782 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77409324-77409841 Neighboring gene Sharpr-MPRA regulatory region 4769 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77505025-77505682 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77528471-77529242 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77529243-77530014 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77544533-77545032 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77645285-77645791 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77655553-77656543 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77657995-77658740 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77665156-77666000 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_47566 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77669291-77669891 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12917 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77673338-77673922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77675499-77676019 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77680917-77681538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:77681539-77682160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:77684903-77685452 Neighboring gene long intergenic non-protein coding RNA 2078 Neighboring gene microRNA 4739

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases. Ungari M, et al. Pathologica, 2021 Dec. PMID 34974547, Free PMC Article
  2. Genetic variants in splicing factor genes and susceptibility to bladder cancer. Wang X, et al. Gene, 2022 Jan 30. PMID 34673209
  3. RBFOX3 Regulates the Chemosensitivity of Cancer Cells to 5-Fluorouracil via the PI3K/AKT, EMT and Cytochrome-C/Caspase Pathways. Liu T, et al. Cell Physiol Biochem, 2018. PMID 29689552
  4. Transforming Growth Factor-β-Induced RBFOX3 Inhibition Promotes Epithelial-Mesenchymal Transition of Lung Cancer Cells. Kim YE, et al. Mol Cells, 2016 Aug 31. PMID 27432190, Free PMC Article
  5. Genetic variants in RBFOX3 are associated with sleep latency. Amin N, et al. Eur J Hum Genet, 2016 Oct. PMID 27142678, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Paclitaxel-induced inhibition of NSCLC invasion and migration via RBFOX3-mediated circIGF1R biogenesis.
    Title: Paclitaxel-induced inhibition of NSCLC invasion and migration via RBFOX3-mediated circIGF1R biogenesis.
  2. Differential Clinical Features in Colombian Patients With Rolandic Epilepsy and Suggestion of Unlikely Association With GRIN2A, RBFOX1, or RBFOX3 Gene Variants.
    Title: Differential Clinical Features in Colombian Patients With Rolandic Epilepsy and Suggestion of Unlikely Association With GRIN2A, RBFOX1, or RBFOX3 Gene Variants.
  3. Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells.
    Title: Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells.
  4. NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases.
    Title: NeuN, a DNA-binding neuron-specific protein expressed by Merkel cell carcinoma: analysis of 15 cases.
  5. Genetic variants in splicing factor genes and susceptibility to bladder cancer.
    Title: Genetic variants in splicing factor genes and susceptibility to bladder cancer.
  6. RBFOX3 knockdown synergized with 5-FU to inhibit the growth and invasion of HCC cells through PI3K/AKT and epithelial-mesenchymal transition (EMT) signaling, and promote apoptosis by activating the cytochrome-c/caspase signaling pathway.
    Title: RBFOX3 Regulates the Chemosensitivity of Cancer Cells to 5-Fluorouracil via the PI3K/AKT, EMT and Cytochrome-C/Caspase Pathways.
  7. In human lung tissue, Claudin-1 is higher in RBFOX3-positive cells than in RBFOX3-negative cells. Immunostaining and mRNA quantification revealed that protein levels, but not mRNA levels, of Claudin-1 are increased by RBFOX3.
    Title: RBFOX3 regulates Claudin-1 expression in human lung tissue via attenuation of proteasomal degradation.
  8. SNPs (rs9900428, rs9907432 and rs7211029) in RBFOX3 associate with sleep latency.
    Title: Genetic variants in RBFOX3 are associated with sleep latency.
  9. this study show that TGF-beta-induced RBFOX3 inhibition plays an important role in epithelial-mesenchymal transition and lung cancer progression
    Title: Transforming Growth Factor-β-Induced RBFOX3 Inhibition Promotes Epithelial-Mesenchymal Transition of Lung Cancer Cells.
  10. NeuN was recently eventually identified as an epitope of Rbfox3. NeuN is highly conserved among species and is stably expressed during specific stages of development. NeuN has been considered to be a reliable marker of mature neurons, however, this role has been challenged by recent studies indicating that NeuN staining is variable and even absent during certain diseases and states. Review.
    Title: Novel Insights into NeuN: from Neuronal Marker to Splicing Regulator.
Submit: New GeneRIF Correction See all GeneRIFs (18)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat downregulates the expression of RBFOX3/NEUN in human neurons PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ44838, FLJ56884, FLJ58356, MGC176616

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA binding protein fox-1 homolog 3
Names
RNA binding protein, fox-1 homolog 3
fox-1 homolog C
hexaribonucleotide binding protein 3
neuN antigen
neuronal nuclei antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053112.2 RefSeqGene

    Range
    59520..581226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001082575.3 → NP_001076044.1  RNA binding protein fox-1 homolog 3 isoform 1

    See identical proteins and their annotated locations for NP_001076044.1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Related
    ENSP00000463653.1, ENST00000580155.5
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  2. NM_001350451.2 → NP_001337380.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Related
    ENSP00000510395.1, ENST00000693108.1
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  3. NM_001350453.2 → NP_001337382.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  4. NM_001385804.1 → NP_001372733.1  RNA binding protein fox-1 homolog 3 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  5. NM_001385805.1 → NP_001372734.1  RNA binding protein fox-1 homolog 3 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  6. NM_001385806.1 → NP_001372735.1  RNA binding protein fox-1 homolog 3 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (4) summary
    PRK13335
    Location:24 → 85
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71 → 231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207 → 343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  7. NM_001385807.1 → NP_001372736.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  8. NM_001385808.1 → NP_001372737.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  9. NM_001385809.1 → NP_001372738.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  10. NM_001385810.1 → NP_001372739.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  11. NM_001385811.1 → NP_001372740.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  12. NM_001385812.1 → NP_001372741.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  13. NM_001385813.1 → NP_001372742.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  14. NM_001385814.1 → NP_001372743.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Related
    ENSP00000497797.1, ENST00000648001.1
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  15. NM_001385815.1 → NP_001372744.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  16. NM_001385816.1 → NP_001372745.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  17. NM_001385817.1 → NP_001372746.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  18. NM_001385818.1 → NP_001372747.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  19. NM_001385819.1 → NP_001372748.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  20. NM_001385820.1 → NP_001372749.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  21. NM_001385821.1 → NP_001372750.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92410.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, A0A8I5KWJ3
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  22. NM_001385822.1 → NP_001372751.1  RNA binding protein fox-1 homolog 3 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92408.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, J3QRF4
    Related
    ENSP00000464186.1, ENST00000583458.5
    Conserved Domains (4) summary
    PRK13335
    Location:24 → 85
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71 → 231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207 → 343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  23. NM_001385823.1 → NP_001372752.1  RNA binding protein fox-1 homolog 3 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92408.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, J3QRF4
    Conserved Domains (4) summary
    PRK13335
    Location:24 → 85
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71 → 231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207 → 343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  24. NM_001385824.1 → NP_001372753.1  RNA binding protein fox-1 homolog 3 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS92409.1
    UniProtKB/TrEMBL
    A0A3B3ITL7, J3QQZ2
    Related
    ENSP00000463964.1, ENST00000582043.5
    Conserved Domains (3) summary
    COG0724
    Location:27 → 133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177 → 313
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99 → 138
    RRM_SF; RNA recognition motif (RRM) superfamily

  25. NM_001385825.1 → NP_001372754.1  RNA binding protein fox-1 homolog 3 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Related
    ENSP00000462007.1, ENST00000584778.5
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  26. NM_001385826.1 → NP_001372755.1  RNA binding protein fox-1 homolog 3 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  27. NM_001385827.1 → NP_001372756.1  RNA binding protein fox-1 homolog 3 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:215 → 304
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  28. NM_001385828.1 → NP_001372757.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  29. NM_001385829.1 → NP_001372758.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  30. NM_001385830.1 → NP_001372759.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  31. NM_001385831.1 → NP_001372760.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  32. NM_001385832.1 → NP_001372761.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  33. NM_001385833.1 → NP_001372762.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  34. NM_001385834.1 → NP_001372763.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  35. NM_001385835.1 → NP_001372764.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  36. NM_001385836.1 → NP_001372765.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  37. NM_001385837.1 → NP_001372766.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  38. NM_001385838.1 → NP_001372767.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  39. NM_001385839.1 → NP_001372768.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  40. NM_001385840.1 → NP_001372769.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  41. NM_001385841.1 → NP_001372770.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  42. NM_001385842.1 → NP_001372771.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3, B4DEG6, B4DF29
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  43. NM_001385843.1 → NP_001372772.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    TIGR01661
    Location:25 → 169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207 → 296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  44. NM_001385844.1 → NP_001372773.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    TIGR01661
    Location:25 → 169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207 → 296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  45. NM_001385845.1 → NP_001372774.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    TIGR01661
    Location:25 → 169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207 → 296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  46. NM_001385846.1 → NP_001372775.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    TIGR01661
    Location:25 → 169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207 → 296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98 → 173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  47. NM_001385847.1 → NP_001372776.1  RNA binding protein fox-1 homolog 3 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    PRK10927
    Location:23 → 155
    PRK10927; cell division protein FtsN
    pfam12414
    Location:159 → 248
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99 → 120
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    79089345..79665571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047435405.1 → XP_047291361.1  RNA binding protein fox-1 homolog 3 isoform X5

  2. XM_017024211.3 → XP_016879700.1  RNA binding protein fox-1 homolog 3 isoform X5

    Conserved Domains (3) summary
    COG0724
    Location:27 → 133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177 → 266
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99 → 138
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. XM_024450593.2 → XP_024306361.1  RNA binding protein fox-1 homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  4. XM_024450592.2 → XP_024306360.1  RNA binding protein fox-1 homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  5. XM_017024208.2 → XP_016879697.1  RNA binding protein fox-1 homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  6. XM_011524366.3 → XP_011522668.1  RNA binding protein fox-1 homolog 3 isoform X3

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    PRK13335
    Location:24 → 85
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00360
    Location:99 → 169
    RRM; RNA recognition motif
    COG0724
    Location:71 → 231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

  7. XM_011524367.3 → XP_011522669.1  RNA binding protein fox-1 homolog 3 isoform X4

    Conserved Domains (3) summary
    COG0724
    Location:27 → 133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177 → 266
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99 → 138
    RRM_SF; RNA recognition motif (RRM) superfamily

  8. XM_017024209.2 → XP_016879698.1  RNA binding protein fox-1 homolog 3 isoform X2

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177 → 313
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99 → 138
    RRM_SF; RNA recognition motif (RRM) superfamily

  9. XM_011524360.2 → XP_011522662.1  RNA binding protein fox-1 homolog 3 isoform X1

    See identical proteins and their annotated locations for XP_011522662.1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  10. XM_024450596.2 → XP_024306364.1  RNA binding protein fox-1 homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

  11. XM_024450595.2 → XP_024306363.1  RNA binding protein fox-1 homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A3B3ITL7
    Conserved Domains (3) summary
    COG0724
    Location:27 → 232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208 → 344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99 → 174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    79984286..80563418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054315132.1 → XP_054171107.1  RNA binding protein fox-1 homolog 3 isoform X5

  2. XM_054315131.1 → XP_054171106.1  RNA binding protein fox-1 homolog 3 isoform X5

  3. XM_054315122.1 → XP_054171097.1  RNA binding protein fox-1 homolog 3 isoform X1

  4. XM_054315125.1 → XP_054171100.1  RNA binding protein fox-1 homolog 3 isoform X1

  5. XM_054315127.1 → XP_054171102.1  RNA binding protein fox-1 homolog 3 isoform X1

  6. XM_054315129.1 → XP_054171104.1  RNA binding protein fox-1 homolog 3 isoform X3

  7. XM_054315130.1 → XP_054171105.1  RNA binding protein fox-1 homolog 3 isoform X4

  8. XM_054315128.1 → XP_054171103.1  RNA binding protein fox-1 homolog 3 isoform X2

  9. XM_054315126.1 → XP_054171101.1  RNA binding protein fox-1 homolog 3 isoform X1

  10. XM_054315124.1 → XP_054171099.1  RNA binding protein fox-1 homolog 3 isoform X1

  11. XM_054315123.1 → XP_054171098.1  RNA binding protein fox-1 homolog 3 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001025448.1: Suppressed sequence

    Description
    NM_001025448.1: This RefSeq was permanently suppressed because it contains the wrong CDS.

  2. NM_001039904.1: Suppressed sequence

    Description
    NM_001039904.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NFN3.4 GenPept UniProtKB/Swiss-Prot:A6NFN3

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