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PF_RS02275 glycoside hydrolase family 1 protein [ Pyrococcus furiosus DSM 3638 ]

Gene ID: 1468283, updated on 22-Oct-2024

Summary

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Gene symbol
PF_RS02275
Gene description
glycoside hydrolase family 1 protein
Locus tag
PF_RS02275
Gene type
protein coding
Organism
Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
Lineage
Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
Old locus tag
PF0442
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Genomic context

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Sequence:
NC_003413.1 (458228..459493)

NC_003413.1Genomic Context describing neighboring genes Neighboring gene vitamin B12-dependent ribonucleotide reductase Neighboring gene galactose-1-phosphate uridylyltransferase Neighboring gene MFS transporter Neighboring gene hydrolase Neighboring gene galactokinase Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003413.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Monomer structure of a hyperthermophilic β-glucosidase mutant forming a dodecameric structure in the crystal form. Nakabayashi M, et al. Acta Crystallogr F Struct Biol Commun, 2014 Jul. PMID 25005077, Free PMC Article
  2. Increased susceptibility of beta-glucosidase from the hyperthermophile Pyrococcus furiosus to thermal inactivation at higher pressures. Bruins ME, et al. FEBS J, 2009 Jan. PMID 19019084
  3. Denaturation of an extremely stable hyperthermophilic protein occurs via a dimeric intermediate. Powers SL, et al. Extremophiles, 2007 Jan. PMID 17072686
  4. Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress. Smith JD, et al. Biochim Biophys Acta, 2005 Aug 31. PMID 16112628
  5. Probing the role of an invariant active site His in family GH1 β-glycosidases. Strazzulli A, et al. J Enzyme Inhib Med Chem, 2019 Dec. PMID 31072150, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Monomer structure of a hyperthermophilic beta-glucosidase mutant forming a dodecameric structure in the crystal form helps to explain its exceptional thermostability.
    Title: Monomer structure of a hyperthermophilic β-glucosidase mutant forming a dodecameric structure in the crystal form.
  2. Stability of beta-glucosidase from the hyperthermophile Pyrococcus furiosus is studied as a function of pressure, temperature and pH
    Title: Increased susceptibility of beta-glucosidase from the hyperthermophile Pyrococcus furiosus to thermal inactivation at higher pressures.
  3. Characterize protein stability/folding.
    Title: Denaturation of an extremely stable hyperthermophilic protein occurs via a dimeric intermediate.
  4. By increasing expression temperature from 30 degrees C up to 40 degrees C, secretion yields increased by as much as 440% per cell to greater than 100 mg/L at 37 degrees C.
    Title: Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress.
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General protein information

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Preferred Names
glycoside hydrolase family 1 protein
WP_011011560.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003413.1 Reference assembly

    Range
    458228..459493
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011011560.1 glycoside hydrolase family 1 protein [Pyrococcus furiosus]

    See identical proteins and their annotated locations for WP_011011560.1

    UniProtKB/TrEMBL
    A0A5C0XM92, E7FI48, I6UNA3, Q7LX07, Q9HHB3
    Conserved Domains (1) summary
    COG2723
    Location:2 → 412
    BglB; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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