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SHLD1 - shieldin complex subunit 1

Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in site of double-strand break. [provided by Alliance of Genome Resources, Oct 2024]

NCBI Orthologs

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genes for:

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Species Gene Architecture aa