Ifi44l interferon-induced protein 44 like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ifi44lprovided by MGI
Official Full Name: interferon-induced protein 44 likeprovided by MGI
Primary source: MGI:MGI:95975
See related: Ensembl:ENSMUSG00000039146 AllianceGenome:MGI:95975
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: H28; H-28; H28-1; NS1178
Summary: This gene encodes a minor histocompatibility antigen that is involved in tissue graft rejection and is polymorphic in different mouse strains. The 5' region of this gene, including the translational start codon and the first 293 amino acids, is absent from the C57BL/6J genome. The encoded antigen is not thought to be expressed in C57BL/6J. [provided by RefSeq, Mar 2013]
Annotation information: Annotation category: partial on reference assembly
Expression: Low expression observed in reference dataset See more
Orthologs: human all
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Genomic context

Location:: 3 H3; 3 76.94 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (151464374..151468528, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (151758737..151762891, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.
Title: Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus.
Data identified Tnni3k, Fpgt and H28 as likely likely candidates for Vms1.
Title: Quantitative trait locus analysis, pathway analysis, and consomic mapping show genetic variants of Tnni3k, Fpgt, or H28 control susceptibility to viral myocarditis.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Spontaneous (1)

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in defense response to virus	ISO Inferred from Sequence Orthology more info
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within immune response	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: interferon-induced protein 44-like

Names: H28c minor histocompatibility antigen 1; histocompatibility 28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.