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gag-pol Gag-Pol [ Human immunodeficiency virus 1 ]

Gene ID: 155348, updated on 21-Mar-2024

Summary

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Gene symbol
gag-pol
Gene description
Gag-Pol
Locus tag
HIV1gp1
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Human immunodeficiency virus 1
Lineage
Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group
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Genomic context

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Sequence:
NC_001802.1 (336..4642)

NC_001802.1Genomic Context describing neighboring genes Neighboring gene Pr55(Gag) Neighboring gene Vif Neighboring gene Vpr Neighboring gene Tat Neighboring gene Rev Neighboring gene Vpu Neighboring gene Envelope surface glycoprotein gp160, precursor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001802.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biophysical Characterization of Novel DNA Aptamers against K103N/Y181C Double Mutant HIV-1 Reverse Transcriptase. Ratanabunyong S, et al. Molecules, 2022 Jan 3. PMID 35011517, Free PMC Article
  2. HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio. Liu S, et al. Retrovirology, 2021 Nov 22. PMID 34809662, Free PMC Article
  3. Changes in dynamic and static structures of the HIV-1 p24 capsid protein N-domain caused by amino-acid substitution are associated with its viral viability. Sato Y, et al. Protein Sci, 2021 Nov. PMID 34523753, Free PMC Article
  4. High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Ha B, et al. Nat Commun, 2021 May 4. PMID 33947853, Free PMC Article
  5. HIV-1 Gag-Pol Sequences from Ugandan Early Infections Reveal Sequence Variants Associated with Elevated Replication Capacity. Kapaata A, et al. Viruses, 2021 Jan 23. PMID 33498793, Free PMC Article

See all (670) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Effect of the L74I Polymorphism on Fitness of Cabotegravir-Resistant Variants of Human Immunodeficiency Virus 1 Subtype A6.
    Title: Effect of the L74I Polymorphism on Fitness of Cabotegravir-Resistant Variants of Human Immunodeficiency Virus 1 Subtype A6.
  2. HIV-1 reverse transcriptase stability correlates with Gag cleavage efficiency: reverse transcriptase interaction implications for modulating protease activation.
    Title: HIV-1 reverse transcriptase stability correlates with Gag cleavage efficiency: reverse transcriptase interaction implications for modulating protease activation.
  3. Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1.
    Title: Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1.
  4. Biophysical Characterization of Novel DNA Aptamers against K103N/Y181C Double Mutant HIV-1 Reverse Transcriptase.
    Title: Biophysical Characterization of Novel DNA Aptamers against K103N/Y181C Double Mutant HIV-1 Reverse Transcriptase.
  5. HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio.
    Title: HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio.
  6. Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design.
    Title: Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design.
  7. Changes in dynamic and static structures of the HIV-1 p24 capsid protein N-domain caused by amino-acid substitution are associated with its viral viability.
    Title: Changes in dynamic and static structures of the HIV-1 p24 capsid protein N-domain caused by amino-acid substitution are associated with its viral viability.
  8. Computational design of small molecular modulators of protein-protein interactions with a novel thermodynamic cycle: Allosteric inhibitors of HIV-1 integrase.
    Title: Computational design of small molecular modulators of protein-protein interactions with a novel thermodynamic cycle: Allosteric inhibitors of HIV-1 integrase.
  9. HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon.
    Title: HIV-1 Integrase Diversity and Resistance-Associated Mutations and Polymorphisms Among Integrase Strand Transfer Inhibitor-Naive HIV-1 Patients from Cameroon.
  10. Influence of the amino-terminal sequence on the structure and function of HIV integrase.
    Title: Influence of the amino-terminal sequence on the structure and function of HIV integrase.
Submit: New GeneRIF Correction See all GeneRIFs (263)

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
ATP-citrate synthase isoform 1 ACLY complexes with PubMed
fatty acid CoA ligase Acsl3 ACSL3 complexes with PubMed
actin, cytoplasmic 1 ACTB complexes with PubMed
double-stranded RNA-specific adenosine deaminase isoform b ADAR complexes with PubMed
apoptosis-inducing factor 1, mitochondrial isoform AIF precursor AIFM1 complexes with PubMed
delta-1-pyrroline-5-carboxylate synthase isoform 1 ALDH18A1 complexes with PubMed
THO complex subunit 4 ALYREF complexes with PubMed
AP-2 complex subunit mu isoform a AP2M1 complexes with PubMed
AP-3 complex subunit delta-1 isoform 2 AP3D1 complexes with PubMed
AP-3 complex subunit sigma-1 isoform 1 AP3S1 complexes with PubMed
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 APOBEC3G interacts with PubMed
APOBEC3G interacts with PubMed
ADP-ribosylation factor 4 ARF4 complexes with PubMed
ADP-ribosylation factor 5 ARF5 complexes with PubMed
ADP-ribosylation factor 6 ARF6 complexes with PubMed
ADP-ribosylation factor-like protein 1 isoform 1 ARL1 complexes with PubMed
actin-related protein 2/3 complex subunit 4 isoform a ARPC4 complexes with PubMed
sodium/potassium-transporting ATPase subunit alpha-1 isoform a ATP1A1 complexes with PubMed
ATP synthase subunit alpha, mitochondrial isoform a precursor ATP5F1A complexes with PubMed
ATP synthase subunit gamma, mitochondrial isoform H (heart) precursor ATP5F1C complexes with PubMed
ATP synthase subunit O, mitochondrial precursor ATP5PO complexes with PubMed
V-type proton ATPase subunit d 1 ATP6V0D1 complexes with PubMed
multifunctional protein CAD isoform 1 CAD complexes with PubMed
calnexin isoform d precursor CANX complexes with PubMed
caprin-1 isoform 1 CAPRIN1 complexes with PubMed
T-complex protein 1 subunit beta isoform 1 CCT2 complexes with PubMed
T-complex protein 1 subunit delta isoform a CCT4 complexes with PubMed
cell division cycle 5-like protein CDC5L complexes with PubMed
CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform 1 CDIPT complexes with PubMed
MHC class II transactivator isoform 2 CIITA upregulates PubMed
clathrin light chain A isoform a CLTA incorporates PubMed
clathrin light chain B isoform a CLTB incorporates PubMed
clathrin heavy chain 1 isoform 1 CLTC complexes with PubMed
CLTC incorporates PubMed
coatomer subunit alpha isoform 2 COPA complexes with PubMed
coatomer subunit zeta-1 isoform 1 COPZ1 complexes with PubMed
copine-3 CPNE3 complexes with PubMed
cleavage and polyadenylation specificity factor subunit 1 CPSF1 complexes with PubMed
cleavage and polyadenylation specificity factor subunit 7 isoform 1 CPSF7 complexes with PubMed
aspartate--tRNA ligase, cytoplasmic isoform 1 DARS1 complexes with PubMed
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor DDOST complexes with PubMed
ATP-dependent RNA helicase DDX1 DDX1 complexes with PubMed
probable ATP-dependent RNA helicase DDX17 isoform 1 precursor DDX17 regulated by PubMed
DDX17 complexes with PubMed
nucleolar RNA helicase 2 isoform 1 DDX21 complexes with PubMed
probable ATP-dependent RNA helicase DDX23 DDX23 complexes with PubMed
probable ATP-dependent RNA helicase DDX27 isoform 2 DDX27 complexes with PubMed
spliceosome RNA helicase DDX39B DDX39B complexes with PubMed
ATP-dependent RNA helicase DDX3X isoform 1 DDX3X complexes with PubMed
probable ATP-dependent RNA helicase DDX5 isoform a DDX5 complexes with PubMed
7-dehydrocholesterol reductase isoform 1 DHCR7 complexes with PubMed
ATP-dependent RNA helicase DHX15 DHX15 complexes with PubMed
ATP-dependent RNA helicase DHX30 isoform 2 DHX30 complexes with PubMed
ATP-dependent RNA helicase A DHX9 regulated by PubMed
DHX9 complexes with PubMed
dynamin-2 isoform 3 DNM2 complexes with PubMed
developmentally-regulated GTP-binding protein 1 DRG1 complexes with PubMed
elongation factor 1-alpha 1 EEF1A1 complexes with PubMed
elongation factor 1-delta isoform 1 EEF1D complexes with PubMed
elongation factor 1-gamma EEF1G complexes with PubMed
eukaryotic translation initiation factor 3 subunit A EIF3A complexes with PubMed
eukaryotic translation initiation factor 3 subunit D EIF3D complexes with PubMed
eukaryotic translation initiation factor 3 subunit E EIF3E complexes with PubMed
eukaryotic initiation factor 4A-I isoform 1 EIF4A1 complexes with PubMed
eukaryotic initiation factor 4A-III isoform 1 EIF4A3 complexes with PubMed
ELAV-like protein 1 ELAVL1 complexes with PubMed
alpha-enolase isoform 1 ENO1 complexes with PubMed
bifunctional glutamate/proline--tRNA ligase EPRS1 complexes with PubMed
eukaryotic peptide chain release factor subunit 1 isoform 1 ETF1 modulated by PubMed
electron transfer flavoprotein subunit beta isoform 1 ETFB complexes with PubMed
fatty acid synthase FASN complexes with PubMed
pre-mRNA 3'-end-processing factor FIP1 isoform 1 FIP1L1 complexes with PubMed
filamin-A isoform 1 FLNA complexes with PubMed
glyceraldehyde-3-phosphate dehydrogenase isoform 1 GAPDH interacts with PubMed
GAPDH complexes with PubMed
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 isoform 1 HACD3 complexes with PubMed
heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 complexes with PubMed
heterogeneous nuclear ribonucleoprotein A1 isoform a HNRNPA1 complexes with PubMed
heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2 HNRNPA2B1 complexes with PubMed
heterogeneous nuclear ribonucleoprotein A3 isoform a HNRNPA3 complexes with PubMed
heterogeneous nuclear ribonucleoprotein A/B isoform b HNRNPAB complexes with PubMed
heterogeneous nuclear ribonucleoproteins C1/C2 isoform b HNRNPC complexes with PubMed
heterogeneous nuclear ribonucleoprotein D0 isoform c HNRNPD complexes with PubMed
heterogeneous nuclear ribonucleoprotein F HNRNPF complexes with PubMed
heterogeneous nuclear ribonucleoprotein H isoform a HNRNPH1 complexes with PubMed
heterogeneous nuclear ribonucleoprotein H2 HNRNPH2 complexes with PubMed
heterogeneous nuclear ribonucleoprotein H3 isoform a HNRNPH3 complexes with PubMed
heterogeneous nuclear ribonucleoprotein K isoform a HNRNPK complexes with PubMed
heterogeneous nuclear ribonucleoprotein M isoform a HNRNPM complexes with PubMed
heterogeneous nuclear ribonucleoprotein R isoform 2 HNRNPR complexes with PubMed
heterogeneous nuclear ribonucleoprotein U isoform b HNRNPU complexes with PubMed
peroxisomal multifunctional enzyme type 2 isoform 2 HSD17B4 complexes with PubMed
heat shock protein HSP 90-alpha isoform 2 HSP90AA1 incorporates PubMed
heat shock protein HSP 90-beta isoform a HSP90AB1 incorporates PubMed
heat shock 70 kDa protein 1A HSPA1A complexes with PubMed
heat shock 70 kDa protein 1B HSPA1B complexes with PubMed
heat shock 70 kDa protein 1-like HSPA1L complexes with PubMed
endoplasmic reticulum chaperone BiP precursor HSPA5 complexes with PubMed
heat shock cognate 71 kDa protein isoform 1 HSPA8 complexes with PubMed
stress-70 protein, mitochondrial precursor HSPA9 complexes with PubMed
60 kDa heat shock protein, mitochondrial HSPD1 complexes with PubMed
E3 ubiquitin-protein ligase HUWE1 HUWE1 interacts with PubMed
isoleucine--tRNA ligase, cytoplasmic isoform 1 IARS1 complexes with PubMed
isocitrate dehydrogenase IDH3A complexes with PubMed
insulin-like growth factor 2 mRNA-binding protein 1 isoform 1 IGF2BP1 complexes with PubMed
insulin-like growth factor 2 mRNA-binding protein 3 IGF2BP3 complexes with PubMed
interleukin enhancer-binding factor 2 isoform 1 ILF2 complexes with PubMed
interleukin enhancer-binding factor 3 isoform b ILF3 complexes with PubMed
alpha-internexin INA complexes with PubMed
importin-7 IPO7 complexes with PubMed
ras GTPase-activating-like protein IQGAP1 IQGAP1 complexes with PubMed
lysine--tRNA ligase isoform 2 KARS1 associates with PubMed
far upstream element-binding protein 2 isoform 1 KHSRP complexes with PubMed
importin subunit beta-1 isoform 1 KPNB1 complexes with PubMed
KRR1 small subunit processome component homolog KRR1 complexes with PubMed
leucine--tRNA ligase, cytoplasmic isoform 1 LARS1 complexes with PubMed
L-lactate dehydrogenase A chain isoform 1 LDHA complexes with PubMed
L-lactate dehydrogenase B chain isoform LDHB LDHB complexes with PubMed
leucine-rich PPR motif-containing protein, mitochondrial precursor LRPPRC complexes with PubMed
leucine-rich repeat-containing protein 59 LRRC59 complexes with PubMed
putative RNA-binding protein Luc7-like 2 isoform 1 LUC7L2 complexes with PubMed
lysozyme C precursor LYZ complexes with PubMed
matrin-3 isoform a MATR3 complexes with PubMed
DNA replication licensing factor MCM7 isoform 1 MCM7 complexes with PubMed
mannosyl-oligosaccharide glucosidase isoform 1 MOGS complexes with PubMed
helicase MOV-10 isoform 1 MOV10 complexes with PubMed
myb-binding protein 1A isoform 2 MYBBP1A complexes with PubMed
nucleolin NCL complexes with PubMed
NF-kappa-B-repressing factor isoform 2 NKRF complexes with PubMed
non-POU domain-containing octamer-binding protein isoform 1 NONO complexes with PubMed
nucleophosmin isoform 1 NPM1 complexes with PubMed
vesicle-fusing ATPase NSF complexes with PubMed
cleavage and polyadenylation specificity factor subunit 5 NUDT21 complexes with PubMed
nuclear pore complex protein Nup155 isoform 2 NUP155 complexes with PubMed
ornithine aminotransferase, mitochondrial isoform 1 precursor OAT complexes with PubMed
polyadenylate-binding protein 1 PABPC1 complexes with PubMed
polyadenylate-binding protein 4 isoform 2 PABPC4 complexes with PubMed
polyadenylate-binding protein 2 isoform 1 PABPN1 complexes with PubMed
poly(rC)-binding protein 1 PCBP1 complexes with PubMed
pyruvate dehydrogenase E1 component subunit beta, mitochondrial isoform 1 precursor PDHB complexes with PubMed
prohibitin 1 isoform 1 PHB1 complexes with PubMed
prohibitin-2 isoform 1 PHB2 complexes with PubMed
pyruvate kinase PKM isoform a PKM complexes with PubMed
plastin-3 isoform 1 PLS3 complexes with PubMed
peroxiredoxin-6 PRDX6 complexes with PubMed
DNA-dependent protein kinase catalytic subunit isoform 1 PRKDC complexes with PubMed
pre-mRNA-processing factor 40 homolog A isoform 1 PRPF40A complexes with PubMed
pre-mRNA-processing-splicing factor 8 PRPF8 complexes with PubMed
26S proteasome regulatory subunit 10B PSMC6 complexes with PubMed
26S proteasome non-ATPase regulatory subunit 2 isoform 1 PSMD2 complexes with PubMed
small ribosomal subunit protein mS39 precursor PTCD3 complexes with PubMed
phosphatidylserine synthase 1 isoform 1 PTDSS1 complexes with PubMed
glycogen phosphorylase, liver form isoform 1 PYGL complexes with PubMed
ras-related protein Rab-10 RAB10 complexes with PubMed
ras-related protein Rab-5C isoform a RAB5C complexes with PubMed
ras-related protein Rab-8A RAB8A complexes with PubMed
small ribosomal subunit protein RACK1 RACK1 complexes with PubMed
GTP-binding nuclear protein Ran isoform 1 RAN complexes with PubMed
ribonucleoprotein PTB-binding 1 RAVER1 complexes with PubMed
RNA-binding motif protein, X chromosome isoform 1 RBMX complexes with PubMed
E3 ubiquitin-protein ligase BRE1A RNF20 complexes with PubMed
large ribosomal subunit protein uL16 isoform a RPL10 complexes with PubMed
large ribosomal subunit protein eL13 isoform 1 RPL13 complexes with PubMed
large ribosomal subunit protein eL14 RPL14 complexes with PubMed
large ribosomal subunit protein uL22 isoform a RPL17 complexes with PubMed
large ribosomal subunit protein eL18 isoform 1 RPL18 complexes with PubMed
large ribosomal subunit protein eL19 isoform 1 RPL19 complexes with PubMed
large ribosomal subunit protein eL24 RPL24 complexes with PubMed
large ribosomal subunit protein eL29 RPL29 complexes with PubMed
large ribosomal subunit protein uL3 isoform a RPL3 complexes with PubMed
large ribosomal subunit protein uL4 RPL4 complexes with PubMed
large ribosomal subunit protein uL18 RPL5 complexes with PubMed
large ribosomal subunit protein eL6 isoform 1 RPL6 complexes with PubMed
large ribosomal subunit protein uL30 isoform 1 RPL7 complexes with PubMed
large ribosomal subunit protein eL8 RPL7A complexes with PubMed
large ribosomal subunit protein uL2 RPL8 complexes with PubMed
large ribosomal subunit protein uL6 RPL9 complexes with PubMed
large ribosomal subunit protein uL10 RPLP0 complexes with PubMed
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor RPN1 complexes with PubMed
small ribosomal subunit protein uS5 RPS2 complexes with PubMed
small ribosomal subunit protein uS3 isoform 1 RPS3 complexes with PubMed
small ribosomal subunit protein eS4, X isoform RPS4X complexes with PubMed
small ribosomal subunit protein eS6 RPS6 complexes with PubMed
small ribosomal subunit protein eS8 RPS8 complexes with PubMed
small ribosomal subunit protein uS4 isoform a RPS9 complexes with PubMed
ras-related GTP-binding protein A RRAGA complexes with PubMed
scaffold attachment factor B1 isoform 3 SAFB complexes with PubMed
U4/U6.U5 tri-snRNP-associated protein 1 SART1 complexes with PubMed
protein transport protein Sec61 subunit alpha isoform 1 isoform 1 SEC61A1 complexes with PubMed
serpin H1 precursor SERPINH1 complexes with PubMed
splicing factor 3B subunit 1 isoform 1 SF3B1 complexes with PubMed
splicing factor 3B subunit 2 SF3B2 complexes with PubMed
splicing factor 3B subunit 4 SF3B4 complexes with PubMed
splicing factor, proline- and glutamine-rich SFPQ complexes with PubMed
sideroflexin-1 isoform 1 SFXN1 complexes with PubMed
mitochondrial 2-oxoglutarate/malate carrier protein isoform 1 SLC25A11 complexes with PubMed
ADP/ATP translocase 2 SLC25A5 complexes with PubMed
structural maintenance of chromosomes protein 1A isoform 1 SMC1A complexes with PubMed
U5 small nuclear ribonucleoprotein 200 kDa helicase SNRNP200 complexes with PubMed
spectrin alpha chain, non-erythrocytic 1 isoform 2 SPTAN1 complexes with PubMed
signal recognition particle subunit SRP68 isoform 1 SRP68 complexes with PubMed
signal recognition particle subunit SRP72 isoform 1 SRP72 complexes with PubMed
signal recognition particle receptor subunit beta SRPRB complexes with PubMed
serine/arginine-rich splicing factor 1 isoform 1 SRSF1 complexes with PubMed
serine/arginine-rich splicing factor 10 isoform 1 SRSF10 complexes with PubMed
serine/arginine-rich splicing factor 4 SRSF4 complexes with PubMed
serine/arginine-rich splicing factor 7 isoform 1 SRSF7 complexes with PubMed
double-stranded RNA-binding protein Staufen homolog 1 isoform a STAU1 complexes with PubMed
heterogeneous nuclear ribonucleoprotein Q isoform 1 SYNCRIP complexes with PubMed
RISC-loading complex subunit TARBP2 isoform b TARBP2 interacts with PubMed
TAR DNA-binding protein 43 TARDBP complexes with PubMed
T-complex protein 1 subunit alpha isoform a TCP1 complexes with PubMed
THO complex subunit 2 THOC2 complexes with PubMed
transcription intermediary factor 1-beta TRIM28 complexes with PubMed
tubulin alpha-1A chain isoform 1 TUBA1A complexes with PubMed
tubulin alpha-4A chain isoform 1 TUBA4A complexes with PubMed
regulator of nonsense transcripts 1 isoform 2 UPF1 complexes with PubMed
regulator of nonsense transcripts 3B isoform 2 UPF3B complexes with PubMed
vimentin VIM complexes with PubMed
Y-box-binding protein 1 YBX1 complexes with PubMed
zinc finger RNA-binding protein ZFR complexes with PubMed
A-kinase anchor protein 8-like isoform 1 AKAP8L incorporates PubMed
anaphase-promoting complex subunit 2 ANAPC2 interacts with PubMed
DNA dC->dU-editing enzyme APOBEC-3F isoform a APOBEC3F interacts with PubMed
beta-arrestin-2 isoform 1 ARRB2 interacts with PubMed
autophagy-related protein 16-1 isoform 2 ATG16L1 interacts with PubMed
protein Atg16l2 isoform 1 ATG16L2 interacts with PubMed
cell cycle and apoptosis regulator protein 2 isoform 1 CCAR2 interacts with PubMed
T-cell surface glycoprotein CD8 alpha chain isoform 1 precursor CD8A inhibits PubMed
T-cell surface glycoprotein CD8 beta chain isoform 5 precursor CD8B inhibits PubMed
CLTA stabilized by PubMed
CLTB stabilized by PubMed
CLTC stabilized by PubMed
EIF3A interacts with PubMed
eukaryotic translation initiation factor 3 subunit B isoform 1 EIF3B interacts with PubMed
eukaryotic translation initiation factor 3 subunit C isoform a EIF3C interacts with PubMed
EIF3D interacts with PubMed
EIF3E interacts with PubMed
eukaryotic translation initiation factor 3 subunit F EIF3F interacts with PubMed
eukaryotic translation initiation factor 3 subunit G EIF3G interacts with PubMed
eukaryotic translation initiation factor 3 subunit H EIF3H interacts with PubMed
eukaryotic translation initiation factor 3 subunit I isoform 1 EIF3I interacts with PubMed
eukaryotic translation initiation factor 3 subunit K isoform 1 EIF3K interacts with PubMed
eukaryotic translation initiation factor 3 subunit L isoform 1 EIF3L interacts with PubMed
ferrochelatase, mitochondrial isoform b precursor FECH interacts with PubMed
growth factor receptor-bound protein 2 isoform 1 GRB2 interacts with PubMed
HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor HLA-A binds PubMed
HSPD1 interacts with PubMed
IDH3A interacts with PubMed
interleukin-10 isoform 1 precursor IL10 regulated by PubMed
IPO7 interacts with PubMed
KARS1 interacts with PubMed
KARS1 binds PubMed
galectin-3-binding protein precursor LGALS3BP interacts with PubMed
LIM domain-containing protein 1 LIMD1 interacts with PubMed
DNA replication licensing factor MCM4 MCM4 interacts with PubMed
DNA replication licensing factor MCM6 MCM6 interacts with PubMed
MCM7 interacts with PubMed
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 1 NFU1 interacts with PubMed
nuclear migration protein nudC NUDC interacts with PubMed
oxysterol-binding protein-related protein 3 isoform a OSBPL3 interacts with PubMed
protein disulfide-isomerase A4 isofrom 2 precursor PDIA4 interacts with PubMed
protein disulfide-isomerase A6 isoform d precursor PDIA6 interacts with PubMed
protein pelota homolog PELO interacts with PubMed
POU domain, class 2, transcription factor 1 isoform 1 POU2F1 interacts with PubMed
POU domain, class 2, transcription factor 2 isoform 2 POU2F2 interacts with PubMed
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB interacts with PubMed
PC4 and SFRS1-interacting protein isoform 1 PSIP1 recruits PubMed
PSIP1 interacts with PubMed
reticulocalbin-1 precursor RCN1 interacts with PubMed
ATP-dependent DNA helicase Q1 RECQL interacts with PubMed
ribonucleoside-diphosphate reductase subunit M2 isoform 2 RRM2 interacts with PubMed
ruvB-like 1 isoform 1 RUVBL1 interacts with PubMed
transcription factor Sp1 isoform b SP1 interacts with PubMed
transcription factor Sp3 isoform 1 SP3 interacts with PubMed
transcription factor PU.1 isoform 2 SPI1 interacts with PubMed
succinate--CoA ligase SUCLG2 interacts with PubMed
5,6-dihydroxyindole-2-carboxylic acid oxidase precursor TYRP1 interacts with PubMed
peroxisomal leader peptide-processing protease isoform a TYSND1 interacts with PubMed
E3 ubiquitin-protein ligase UBR2 isoform 1 UBR2 interacts with PubMed
E3 ubiquitin-protein ligase UBR4 UBR4 interacts with PubMed
ATP-dependent translocase ABCB1 isoform 2 ABCB1 interacts with PubMed
disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein ADAM10 co-localizes with PubMed
alkaline phosphatase, placental type preproprotein ALPP interacts with PubMed
ankyrin repeat domain-containing protein 13C ANKRD13C interacts with PubMed
APOBEC3F interacts with PubMed
APOBEC3G binds PubMed
APOBEC3G interacts with PubMed
APOBEC3G interacts with PubMed
APOBEC3G complexes with PubMed
serine-protein kinase ATM isoform a ATM interacts with PubMed
ATM interacts with PubMed
V-type proton ATPase subunit G 3 isoform a ATP6V1G3 interacts with PubMed
serine/threonine-protein kinase ATR isoform 1 ATR interacts with PubMed
transcription regulator protein BACH2 BACH2 interacts with PubMed
barrier-to-autointegration factor BANF1 interacts with PubMed
BANF1 interacts with PubMed
transcription factor BTF3 isoform B BTF3 binds PubMed
C2 domain-containing protein 3 isoform 2 C2CD3 interacts with PubMed
cullin-associated NEDD8-dissociated protein 2 isoform 2 CAND2 interacts with PubMed
coiled-coil domain-containing protein 32 isoform 2 CCDC32 binds PubMed
CCT4 binds PubMed
cell division cycle-associated 7-like protein isoform 1 CDCA7L co-localizes with PubMed
CDCA7L binds PubMed
CDCA7L overlaps PubMed
CDCA7L binds PubMed
cyclin-dependent kinase inhibitor 1 isoform 1 CDKN1A complexes with PubMed
choline/ethanolaminephosphotransferase 1 isoform 1 CEPT1 interacts with PubMed
probable cytosolic iron-sulfur protein assembly protein CIAO1 CIAO1 interacts with PubMed
cytosolic iron-sulfur assembly component 2B CIAO2B interacts with PubMed
cytoskeleton-associated protein 5 isoform b CKAP5 interacts with PubMed
creatine kinase U-type, mitochondrial isoform 1 precursor CKMT1A interacts with PubMed
creatine kinase U-type, mitochondrial precursor CKMT1B interacts with PubMed
CLTA incorporates PubMed
CLTA incorporates PubMed
CLTB incorporates PubMed
CLTB incorporates PubMed
CLTC incorporates PubMed
CLTC incorporates PubMed
CREB-binding protein isoform a CREBBP interacts with PubMed
gamma-crystallin S CRYGS interacts with PubMed
exportin-2 isoform 1 CSE1L binds PubMed
cystatin-C precursor CST3 interacts with PubMed
interleukin-8 isoform 1 precursor CXCL8 interacts with PubMed
CXCL8 interacts with PubMed
death domain-associated protein 6 isoform a DAXX interacts with PubMed
DAXX interacts with PubMed
probable ATP-dependent RNA helicase DDX6 isoform 1 DDX6 interacts with PubMed
desmoplakin isoform I DSP interacts with PubMed
dynein light chain 1, cytoplasmic DYNLL1 interacts with PubMed
DYNLL1 interacts with PubMed
DYNLL1 interacts with PubMed
DYNLL1 interacts with PubMed
polycomb protein EED isoform a EED binds PubMed
EED interacts with PubMed
EED stimulated by PubMed
EEF1A1 interacts with PubMed
EEF1A1 binds PubMed
EEF1A1 binds PubMed
EEF1G interacts with PubMed
eIF-2-alpha kinase GCN2 EIF2AK4 binds PubMed
EIF3H binds PubMed
emerin EMD interacts with PubMed
histone acetyltransferase p300 isoform 1 EP300 acetylated by PubMed
EP300 acetylated by PubMed
tumor necrosis factor receptor superfamily member 6 isoform 1 precursor FAS interacts with PubMed
flap endonuclease 1 FEN1 stimulates PubMed
fibrous sheath-interacting protein 1 FSIP1 interacts with PubMed
gem-associated protein 2 isoform alpha GEMIN2 interacts with PubMed
GEMIN2 interacts with PubMed
GEMIN2 binds PubMed
histone H2AX H2AX induces phosphorylation of PubMed
histone deacetylase 1 HDAC1 complexes with PubMed
HDAC1 complexes with PubMed
5'-deoxynucleotidase HDDC2 HDDC2 interacts with PubMed
hepatoma-derived growth factor-related protein 2 isoform 2 HDGFL2 activated by PubMed
HDGFL2 interacts with PubMed
HDGFL2 interacts with PubMed
HDGFL2 co-localizes with PubMed
HEAT repeat-containing protein 1 HEATR1 interacts with PubMed
high mobility group protein HMG-I/HMG-Y isoform b HMGA1 stimulated by PubMed
non-histone chromosomal protein HMG-17 HMGN2 binds PubMed
HNRNPA2B1 binds PubMed
HNRNPM interacts with PubMed
heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform a HNRNPUL1 interacts with PubMed
HORMA domain-containing protein 2 isoform a HORMAD2 interacts with PubMed
HSPD1 stimulated by PubMed
10 kDa heat shock protein, mitochondrial HSPE1 interacts with PubMed
HUWE1 interacts with PubMed
zinc finger protein Aiolos isoform 1 IKZF3 interacts with PubMed
interleukin-15 isoform 1 preproprotein IL15 enhanced by PubMed
interleukin-1 beta proprotein IL1B interacts with PubMed
interleukin-2 precursor IL2 enhanced by PubMed
interleukin-4 isoform 1 precursor IL4 enhanced by PubMed
interleukin-7 isoform 1 precursor IL7 interacts with PubMed
IL7 enhanced by PubMed
importin-4 IPO4 interacts with PubMed
importin-5 IPO5 imported by PubMed
IPO5 binds PubMed
IPO5 imported by PubMed
IPO7 binds PubMed
IPO7 imported by PubMed
protein IWS1 homolog isoform 1 IWS1 binds PubMed
IWS1 displaces PubMed
IWS1 overlaps PubMed
histone acetyltransferase KAT2A isoform 1 KAT2A binds PubMed
KAT2A acetylated by PubMed
histone acetyltransferase KAT6A isoform 1 KAT6A acetylated by PubMed
histone acetyltransferase KAT6B isoform 1 KAT6B acetylated by PubMed
histone acetyltransferase KAT7 isoform 1 KAT7 acetylated by PubMed
histone acetyltransferase KAT8 isoform 1 KAT8 acetylated by PubMed
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 isoform 1 KCTD13 interacts with PubMed
dyslexia-associated protein KIAA0319-like protein KIAA0319L interacts with PubMed
kinesin-associated protein 3 isoform 1 KIFAP3 binds PubMed
histone-lysine N-methyltransferase 2A isoform 1 KMT2A binds PubMed
importin subunit alpha-5 KPNA1 interacts with PubMed
KPNA1 complexes with PubMed
KPNA1 imported by PubMed
KPNA1 binds PubMed
KPNA1 imported by PubMed
importin subunit alpha-1 KPNA2 imported by PubMed
KPNA2 interacts with PubMed
KPNA2 interacts with PubMed
KPNA2 complexes with PubMed
KPNA2 imported by PubMed
KPNA2 binds PubMed
importin subunit alpha-4 KPNA3 imported by PubMed
KPNA3 interacts with PubMed
KPNA3 complexes with PubMed
KPNA3 imported by PubMed
KPNA3 binds PubMed
importin subunit alpha-3 KPNA4 binds PubMed
KPNA4 interacts with PubMed
KPNA4 binds PubMed
KPNA4 complexes with PubMed
KPNA4 imported by PubMed
KPNA4 binds PubMed
KPNA4 imported by PubMed
importin subunit alpha-6 isoform b KPNA5 interacts with PubMed
KPNA5 complexes with PubMed
KPNA5 imported by PubMed
KPNA5 binds PubMed
KPNA5 imported by PubMed
importin subunit alpha-7 KPNA6 imported by PubMed
KPNA6 imported by PubMed
KPNA6 binds PubMed
KPNB1 interacts with PubMed
KPNB1 imported by PubMed
KPNB1 binds PubMed
KPNB1 imported by PubMed
LRPPRC associates with PubMed
mitogen-activated protein kinase 1 MAPK1 interacts with PubMed
mitogen-activated protein kinase 8 isoform beta2 MAPK8 phosphorylated by PubMed
MCM6 interacts with PubMed
myocardin-related transcription factor B isoform 2 MRTFB interacts with PubMed
interferon-induced GTP-binding protein Mx2 MX2 interacts with PubMed
NACHT, LRR and PYD domains-containing protein 3 isoform a NLRP3 interacts with PubMed
nuclear pore complex protein Nup153 isoform 2 NUP153 interacts with PubMed
NUP153 interacts with PubMed
NUP153 interacts with PubMed
NUP153 binds PubMed
nuclear pore glycoprotein p62 NUP62 binds PubMed
nuclear pore complex protein Nup98-Nup96 isoform 1 precursor NUP98 cooperates with PubMed
nuclear transport factor 2 NUTF2 inhibited by PubMed
succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial isoform 3 precursor OXCT1 interacts with PubMed
polyadenylate-binding protein 1-like PABPC1L interacts with PubMed
poly PARP1 requires PubMed
phosphoenolpyruvate carboxykinase, cytosolic PCK1 binds PubMed
PDIA4 interacts with PubMed
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 binds PubMed
PIN1 binds PubMed
plakophilin-4 isoform a PKP4 interacts with PubMed
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 isoform 2 precursor PLOD1 interacts with PubMed
procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform 2 precursor PLOD2 interacts with PubMed
protein PML isoform 1 PML interacts with PubMed
pogo transposable element with ZNF domain isoform 1 POGZ binds PubMed
POGZ overlaps PubMed
POGZ displaces PubMed
POGZ competes with PubMed
peptidyl-prolyl cis-trans isomerase A isoform 1 PPIA incorporates PubMed
PRKDC interacts with PubMed
PRKDC interacts with PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 overlaps PubMed
PSIP1 interacts with PubMed
PSIP1 co-localizes with PubMed
PSIP1 stimulated by PubMed
PSIP1 fractionates with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 competes with PubMed
PSIP1 stabilized by PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 induces accumulation of PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 complexes with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 upregulates PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 inhibited by PubMed
PSIP1 imported by PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 binds PubMed
PSIP1 regulated by PubMed
PSIP1 binds PubMed
PSIP1 interacts with PubMed
PSIP1 complexes with PubMed
PSIP1 complexes with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 complexes with PubMed
PSIP1 complexes with PubMed
PSIP1 complexes with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
PSIP1 interacts with PubMed
proteasome subunit alpha type-2 PSMA2 degraded by PubMed
proteasome subunit alpha type-3 isoform 1 PSMA3 degraded by PubMed
proteasome subunit alpha type-5 isoform 1 PSMA5 degraded by PubMed
proteasome subunit alpha type-6 isoform a PSMA6 degraded by PubMed
proteasome subunit alpha type-7 PSMA7 degraded by PubMed
proteasome subunit beta type-1 PSMB1 degraded by PubMed
proteasome subunit beta type-10 PSMB10 degraded by PubMed
proteasome subunit beta type-2 isoform 1 PSMB2 degraded by PubMed
proteasome subunit beta type-3 PSMB3 degraded by PubMed
proteasome subunit beta type-4 PSMB4 degraded by PubMed
proteasome subunit beta type-5 isoform 1 PSMB5 degraded by PubMed
proteasome subunit beta type-6 isoform 1 PSMB6 degraded by PubMed
proteasome subunit beta type-7 precursor PSMB7 degraded by PubMed
proteasome subunit beta type-8 isoform E1 PSMB8 degraded by PubMed
26S proteasome regulatory subunit 4 isoform a PSMC1 degraded by PubMed
26S proteasome regulatory subunit 7 isoform 1 PSMC2 degraded by PubMed
26S proteasome regulatory subunit 6A PSMC3 degraded by PubMed
26S proteasome regulatory subunit 6B isoform 1 PSMC4 degraded by PubMed
26S proteasome regulatory subunit 8 isoform 1 PSMC5 degraded by PubMed
PSMC6 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 1 isoform 1 PSMD1 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 10 isoform 1 PSMD10 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 11 PSMD11 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 12 isoform 1 PSMD12 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 13 isoform 1 PSMD13 degraded by PubMed
PSMD2 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 3 PSMD3 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 4 isoform 2 PSMD4 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 5 isoform 1 PSMD5 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 6 isoform 2 PSMD6 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 7 PSMD7 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 8 PSMD8 degraded by PubMed
26S proteasome non-ATPase regulatory subunit 9 isoform 1 PSMD9 degraded by PubMed
proteasome activator complex subunit 1 isoform 1 PSME1 degraded by PubMed
proteasome activator complex subunit 2 PSME2 degraded by PubMed
proteasome activator complex subunit 3 isoform 1 PSME3 degraded by PubMed
proteasome activator complex subunit 4 PSME4 degraded by PubMed
proteasome inhibitor PI31 subunit isoform 1 PSMF1 degraded by PubMed
E3 ubiquitin-protein ligase RAD18 RAD18 interacts with PubMed
DNA repair protein RAD51 homolog 1 isoform 1 RAD51 inhibited by PubMed
RAD51 inhibited by PubMed
RAN inhibited by PubMed
E3 SUMO-protein ligase RanBP2 isoform 1 RANBP2 interacts with PubMed
ran-binding protein 6 isoform 1 RANBP6 interacts with PubMed
ran-binding protein 9 RANBP9 binds PubMed
putative RNA-binding protein 15B RBM15B interacts with PubMed
ret finger protein-like 3 isoform 2 RFPL3 interacts with PubMed
large ribosomal subunit protein uL14 RPL23 binds PubMed
histone deacetylase complex subunit SAP18 isoform 1 SAP18 binds PubMed
SAP18 binds PubMed
paired amphipathic helix protein Sin3a SIN3A recruits PubMed
superkiller complex protein 8 isoform a SKIC8 interacts with PubMed
zinc transporter 7 SLC30A7 interacts with PubMed
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform a SMARCB1 interacts with PubMed
SMARCB1 inhibited by PubMed
SMARCB1 complexes with PubMed
SMARCB1 interacts with PubMed
SMARCB1 binds PubMed
SMARCB1 stimulated by PubMed
SMARCB1 binds PubMed
SMARCB1 interacts with PubMed
SMARCB1 interacts with PubMed
SMARCB1 recruits PubMed
SMARCB1 interacts with PubMed
SMARCB1 inhibited by PubMed
SMARCB1 binds PubMed
SMARCB1 stimulated by PubMed
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase isoform a precursor ST8SIA4 interacts with PubMed
signal transducer and activator of transcription 5B STAT5B interacts with PubMed
stathmin isoform a STMN1 binds PubMed
SUCLG2 interacts with PubMed
small ubiquitin-related modifier 1 isoform a precursor SUMO1 sumoylated by PubMed
SUMO1 interacts with PubMed
small ubiquitin-related modifier 2 isoform a precursor SUMO2 sumoylated by PubMed
SUMO2 interacts with PubMed
small ubiquitin-related modifier 3 isoform 1 precursor SUMO3 sumoylated by PubMed
tyrosyl-DNA phosphodiesterase 2 TDP2 interacts with PubMed
thyroid hormone receptor-associated protein 3 isoform 1 THRAP3 binds PubMed
tumor necrosis factor ligand superfamily member 13B isoform 1 TNFSF13B interacts with PubMed
transportin-1 isoform 1 TNPO1 imported by PubMed
TNPO1 binds PubMed
TNPO1 imported by PubMed
transportin-3 isoform 1 TNPO3 binds PubMed
TNPO3 binds PubMed
TNPO3 interacts with PubMed
TNPO3 binds PubMed
TNPO3 binds PubMed
TNPO3 binds PubMed
TNPO3 complexes with PubMed
cellular tumor antigen p53 isoform a TP53 induces phosphorylation of PubMed
trafficking protein particle complex subunit 10 isoform a TRAPPC10 interacts with PubMed
TRIM28 inhibited by PubMed
TRIM28 interacts with PubMed
TUBA1A interacts with PubMed
tubulin alpha-1B chain TUBA1B interacts with PubMed
tubulin alpha-1C chain isoform c TUBA1C interacts with PubMed
tubulin alpha-3C chain TUBA3C interacts with PubMed
tubulin alpha-3D chain TUBA3D interacts with PubMed
tubulin alpha-3E chain TUBA3E interacts with PubMed
TUBA4A interacts with PubMed
tubulin alpha-8 chain isoform 1 TUBA8 interacts with PubMed
TYSND1 interacts with PubMed
ubiquitin-like modifier-activating enzyme 1 UBA1 interacts with PubMed
ubiquitin-conjugating enzyme E2 D2 isoform 1 UBE2D2 interacts with PubMed
SUMO-conjugating enzyme UBC9 UBE2I interacts with PubMed
protein unc-45 homolog A isoform 2 UNC45A interacts with PubMed
uracil-DNA glycosylase isoform UNG2 UNG incorporates PubMed
UNG binds PubMed
prefoldin subunit 3 isoform 1 VBP1 binds PubMed
X-ray repair cross-complementing protein 5 XRCC5 associates with PubMed
XRCC5 interacts with PubMed
X-ray repair cross-complementing protein 6 isoform 1 XRCC6 stabilized by PubMed
XRCC6 binds PubMed
XRCC6 associates with PubMed
XRCC6 interacts with PubMed
14-3-3 protein beta/alpha YWHAB interacts with PubMed
14-3-3 protein epsilon YWHAE interacts with PubMed
14-3-3 protein gamma YWHAG interacts with PubMed
14-3-3 protein zeta/delta YWHAZ interacts with PubMed
transcriptional repressor protein YY1 YY1 binds PubMed
alpha-2-macroglobulin isoform a precursor A2M cleaves PubMed
actin, alpha skeletal muscle ACTA1 cleaves PubMed
ACTA1 cleaves PubMed
actin, aortic smooth muscle isoform 1 ACTA2 cleaves PubMed
ACTA2 cleaves PubMed
ACTB cleaves PubMed
ACTB cleaves PubMed
actin, alpha cardiac muscle 1 isoform 1 ACTC1 cleaves PubMed
ACTC1 cleaves PubMed
actin, cytoplasmic 2 ACTG1 cleaves PubMed
ACTG1 cleaves PubMed
actin, gamma-enteric smooth muscle isoform 1 precursor ACTG2 cleaves PubMed
ACTG2 cleaves PubMed
alpha-actinin-1 isoform b ACTN1 cleaves PubMed
adenosylhomocysteinase isoform 1 AHCY interacts with PubMed
A-kinase anchor protein 8 AKAP8 cleaves PubMed
A-kinase anchor protein 9 isoform 2 AKAP9 interacts with PubMed
A-kinase-interacting protein 1 isoform a AKIP1 interacts with PubMed
fructose-bisphosphate aldolase A isoform 1 ALDOA cleaves PubMed
centrosome-associated protein ALMS1 isoform 1 ALMS1 interacts with PubMed
AMP deaminase 2 isoform 1 AMPD2 cleaves PubMed
anaphase-promoting complex subunit 1 ANAPC1 interacts with PubMed
ANAPC2 interacts with PubMed
acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1 ANP32E cleaves PubMed
amyloid-beta precursor protein isoform a precursor APP cleaves PubMed
rho guanine nucleotide exchange factor 12 isoform 1 ARHGEF12 interacts with PubMed
ARRB2 interacts with PubMed
ATP5F1A cleaves PubMed
apoptosis regulator BAX isoform beta BAX interacts with PubMed
BAX cleaves PubMed
apoptosis regulator Bcl-2 isoform alpha BCL2 interacts with PubMed
BCL2 cleaves PubMed
BCL2 downregulates PubMed
protein bicaudal D homolog 2 isoform 2 BICD2 interacts with PubMed
BH3-interacting domain death agonist isoform 1 BID induces cleavage of PubMed
protein BUD31 homolog BUD31 cleaves PubMed
ashwin isoform 1 C2orf49 cleaves PubMed
carbonic anhydrase 12 isoform 1 precursor CA12 cleaves PubMed
calmodulin-1 isoform 2 CALM1 cleaves PubMed
histone-arginine methyltransferase CARM1 isoform 1 CARM1 interacts with PubMed
caspase-3 isoform a preproprotein CASP3 cleaves PubMed
CASP3 activates PubMed
caspase-8 isoform 1 precursor CASP8 cleaves PubMed
CASP8 activates PubMed
caspase-9 isoform alpha precursor CASP9 activates PubMed
coiled-coil and C2 domain-containing protein 1A isoform 1 CC2D1A cleaves PubMed
CCAR2 interacts with PubMed
coiled-coil domain-containing protein 43 isoform 1 CCDC43 cleaves PubMed
C-C chemokine receptor type 10 CCR10 cleaves PubMed
CDC5L cleaves PubMed
CIITA cooperates with PubMed
casein kinase II subunit alpha isoform a CSNK2A1 phosphorylated by PubMed
casein kinase II subunit alpha' CSNK2A2 phosphorylated by PubMed
casein kinase II subunit beta isoform 1 CSNK2B phosphorylated by PubMed
CST3 inhibited by PubMed
CST3 interacts with PubMed
transcriptional repressor CTCF isoform 1 CTCF cleaves PubMed
catenin beta-1 isoform 1 CTNNB1 cleaves PubMed
cytochrome c CYCS interacts with PubMed
CYCS induces release of PubMed
DDX17 cleaves PubMed
ATP-dependent RNA helicase DDX18 DDX18 cleaves PubMed
DDX5 cleaves PubMed
desmin isoform 1 DES cleaves PubMed
DNA fragmentation factor subunit alpha isoform 1 DFFA induces cleavage of PubMed
DNA fragmentation factor subunit beta isoform 2 DFFB induces cleavage of PubMed
pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform 1 DHX16 cleaves PubMed
protein diaphanous homolog 1 isoform 1 DIAPH1 cleaves PubMed
DIAPH1 interacts with PubMed
dihydrolipoyl dehydrogenase, mitochondrial isoform 1 precursor DLD cleaves PubMed
dnaJ homolog subfamily C member 7 isoform 1 DNAJC7 cleaves PubMed
dnaJ homolog subfamily C member 8 DNAJC8 cleaves PubMed
deoxyhypusine hydroxylase DOHH interacts with PubMed
docking protein 1 isoform a DOK1 interacts with PubMed
deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 2 DUT cleaves PubMed
probable rRNA-processing protein EBP2 isoform 2 EBNA1BP2 cleaves PubMed
eukaryotic translation elongation factor 1 epsilon-1 isoform 1 EEF1E1 cleaves PubMed
EEF1G cleaves PubMed
elongation factor 2 EEF2 cleaves PubMed
EIF2AK4 cleaves PubMed
EIF2AK4 cleaves PubMed
EIF3A interacts with PubMed
EIF3B interacts with PubMed
EIF3C interacts with PubMed
EIF3D cleaves PubMed
EIF3D cleaves PubMed
EIF3D interacts with PubMed
EIF3E interacts with PubMed
EIF3F interacts with PubMed
EIF3H interacts with PubMed
EIF3K interacts with PubMed
EIF3L interacts with PubMed
eukaryotic translation initiation factor 3 subunit M isoform 1 EIF3M interacts with PubMed
eukaryotic initiation factor 4A-II EIF4A2 cleaves PubMed
eukaryotic translation initiation factor 4 gamma 1 isoform 5 EIF4G1 cleaves PubMed
eukaryotic translation initiation factor 5A-1 isoform B EIF5A cleaves PubMed
echinoderm microtubule-associated protein-like 3 isoform 3 EML3 interacts with PubMed
ENO1 cleaves PubMed
epiplakin EPPK1 interacts with PubMed
S-formylglutathione hydrolase ESD cleaves PubMed
peptidyl-prolyl cis-trans isomerase FKBP4 FKBP4 cleaves PubMed
FKBP4 interacts with PubMed
FAD synthase isoform 1 FLAD1 interacts with PubMed
folliculin isoform 1 FLCN interacts with PubMed
FLNA cleaves PubMed
filamin-B isoform 2 FLNB cleaves PubMed
filamin-C isoform a FLNC cleaves PubMed
fibronectin isoform 1 precursor FN1 cleaves PubMed
folliculin-interacting protein 1 isoform 1 FNIP1 interacts with PubMed
forkhead box protein C1 FOXC1 interacts with PubMed
cyclin-G-associated kinase isoform 1 GAK interacts with PubMed
glial fibrillary acidic protein isoform 1 GFAP cleaves PubMed
GDP-L-fucose synthase isoform 2 GFUS cleaves PubMed
glutaredoxin 2 isoform 1 GLRX2 activated by PubMed
glutaredoxin-related protein 5, mitochondrial precursor GLRX5 activated by PubMed
guanine nucleotide-binding protein-like 3 isoform 1 GNL3 cleaves PubMed
golgin subfamily A member 1 GOLGA1 interacts with PubMed
probable G-protein coupled receptor 25 GPR25 cleaves PubMed
glutathione reductase, mitochondrial isoform 1 precursor GSR cleaves PubMed
E3 ubiquitin-protein ligase HERC2 HERC2 interacts with PubMed
protein HGH1 homolog HGH1 interacts with PubMed
HNRNPA1 cleaves PubMed
HNRNPA2B1 cleaves PubMed
heterogeneous nuclear ribonucleoprotein L isoform a HNRNPL cleaves PubMed
HNRNPU cleaves PubMed
HSP90AA1 cleaves PubMed
HSP90AB1 cleaves PubMed
HSPD1 cleaves PubMed
HUWE1 cleaves PubMed
intraflagellar transport protein 122 homolog isoform 3 IFT122 interacts with PubMed
IL1B cleaves PubMed
integrin alpha-3 preproprotein ITGA3 cleaves PubMed
integrin beta-4 isoform 1 precursor ITGB4 cleaves PubMed
KARS1 inhibited by PubMed
potassium channel subfamily K member 6 KCNK6 cleaves PubMed
BTB/POZ domain-containing protein KCTD7 isoform 1 KCTD7 cleaves PubMed
KRR1 cleaves PubMed
plastin-2 LCP1 cleaves PubMed
leucine-rich repeat-containing G-protein coupled receptor 6 isoform 2 LGR6 cleaves PubMed
LIMD1 interacts with PubMed
microtubule-associated protein 1A isoform 1 MAP1A cleaves PubMed
microtubule-associated proteins 1A/1B light chain 3A isoform a MAP1LC3A cleaves PubMed
microtubule-associated proteins 1A/1B light chain 3B MAP1LC3B cleaves PubMed
microtubule-associated proteins 1A/1B light chain 3C MAP1LC3C cleaves PubMed
microtubule-associated protein 2 isoform 1 MAP2 cleaves PubMed
induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1 MCL1 interacts with PubMed
DNA replication licensing factor MCM5 MCM5 cleaves PubMed
malate dehydrogenase, mitochondrial isoform 1 precursor MDH2 cleaves PubMed
DNA mismatch repair protein Msh2 isoform 1 MSH2 interacts with PubMed
protein LYRIC isoform 1 MTDH cleaved by PubMed
myosin-10 isoform 2 MYH10 cleaves PubMed
myosin-11 isoform SM1A MYH11 cleaves PubMed
myosin-13 MYH13 cleaves PubMed
myosin-14 isoform 2 MYH14 cleaves PubMed
myosin-6 MYH6 cleaves PubMed
myosin-7 MYH7 cleaves PubMed
myosin-9 MYH9 cleaves PubMed
nuclear prelamin A recognition factor isoform a NARF interacts with PubMed
nuclear autoantigenic sperm protein isoform 2 NASP cleaves PubMed
protein NDRG1 isoform 1 NDRG1 cleaves PubMed
nuclear factor of activated T-cells 5 isoform c NFAT5 interacts with PubMed
nuclear factor NF-kappa-B p105 subunit isoform 1 NFKB1 cleaves PubMed
NFU1 interacts with PubMed
nuclear transcription factor Y subunit alpha isoform 1 NFYA cleaves PubMed
H/ACA ribonucleoprotein complex subunit 2 isoform a NHP2 cleaves PubMed
MKI67 FHA domain-interacting nucleolar phosphoprotein NIFK cleaves PubMed
NKRF cleaves PubMed
NONO cleaves PubMed
puromycin-sensitive aminopeptidase isoform 1 NPEPPS cleaves PubMed
nuclear mitotic apparatus protein 1 isoform 1 NUMA1 cleaves PubMed
OSBPL3 interacts with PubMed
oxysterol-binding protein-related protein 6 isoform a OSBPL6 interacts with PubMed
deubiquitinase OTUD6B isoform 1 OTUD6B cleaves PubMed
proliferation-associated protein 2G4 PA2G4 cleaves PubMed
PABPC1 cleaves PubMed
PABPC1 cleaves PubMed
polyadenylate-binding protein 3 PABPC3 cleaves PubMed
PABPC4 cleaves PubMed
polyadenylate-binding protein 5 PABPC5 cleaves PubMed
PARP1 cleaves PubMed
PARP1 cleaves PubMed
PARP1 induces cleavage of PubMed
protein mono-ADP-ribosyltransferase PARP4 PARP4 interacts with PubMed
PARP4 cleaves PubMed
PARP4 induces cleavage of PubMed
protocadherin gamma-A6 isoform 1 precursor PCDHGA6 cleaves PubMed
protein disulfide-isomerase A3 precursor PDIA3 cleaves PubMed
phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform 1 PHKA1 cleaves PubMed
phosphorylase b kinase regulatory subunit alpha, liver isoform PHKA2 cleaves PubMed
phosphorylase b kinase regulatory subunit beta isoform a PHKB cleaves PubMed
elafin preproprotein PI3 inhibited by PubMed
PKM cleaves PubMed
plastin-1 PLS1 cleaves PubMed
PLS3 cleaves PubMed
phosphomannomutase 2 PMM2 cleaves PubMed
DNA polymerase epsilon catalytic subunit A POLE interacts with PubMed
DNA polymerase epsilon subunit 3 POLE3 interacts with PubMed
DNA polymerase epsilon subunit 4 POLE4 interacts with PubMed
POTE ankyrin domain family member F POTEF cleaves PubMed
platelet basic protein preproprotein PPBP cleaves PubMed
PPIA cleaves PubMed
peptidyl-prolyl cis-trans isomerase H isoform 1 PPIH cleaves PubMed
peroxiredoxin-1 PRDX1 cleaves PubMed
peroxiredoxin-2 PRDX2 cleaves PubMed
protein kinase C alpha type PRKCA inhibited by PubMed
protein kinase C beta type isoform 2 PRKCB inhibited by PubMed
protein kinase C delta type isoform c PRKCD inhibited by PubMed
protein kinase C epsilon type PRKCE inhibited by PubMed
protein kinase C gamma type isoform 2 PRKCG inhibited by PubMed
protein kinase C eta type PRKCH inhibited by PubMed
protein kinase C iota type PRKCI inhibited by PubMed
protein kinase C theta type isoform 1 PRKCQ inhibited by PubMed
protein kinase C zeta type isoform 1 PRKCZ inhibited by PubMed
serine/threonine-protein kinase PRP4 homolog PRP4K cleaves PubMed
PSIP1 cleaves PubMed
PSMA6 cleaves PubMed
proteasome subunit beta type-9 precursor PSMB9 cleaves PubMed
PSMC4 cleaves PubMed
polypyrimidine tract-binding protein 1 isoform a PTBP1 cleaves PubMed
pumilio homolog 2 isoform 1 PUM2 interacts with PubMed
KH domain-containing RNA-binding protein QKI isoform 1 QKI cleaves PubMed
RNA-binding protein 28 isoform 1 RBM28 cleaves PubMed
RNA-binding protein 8A RBM8A cleaves PubMed
regulator of chromosome condensation isoform c RCC1 cleaves PubMed
protein RCC2 RCC2 cleaves PubMed
antiviral innate immune response receptor RIG-I isoform 1 RIGI relocalizes PubMed
receptor-interacting serine/threonine-protein kinase 1 isoform 2 RIPK1 disrupts PubMed
RIPK1 cleaves PubMed
RIPK1 cleaves PubMed
RIPK1 binds PubMed
receptor-interacting serine/threonine-protein kinase 2 isoform 1 RIPK2 cleaves PubMed
RIPK2 binds PubMed
ribonuclease inhibitor RNH1 cleaves PubMed
RPL10 cleaves PubMed
large ribosomal subunit protein eL20 RPL18A cleaves PubMed
RPL23 cleaves PubMed
RPL3 cleaves PubMed
large ribosomal subunit protein eL30 RPL30 cleaves PubMed
large ribosomal subunit protein uL29 RPL35 cleaves PubMed
RPL5 cleaves PubMed
RPL6 cleaves PubMed
RPL7 cleaves PubMed
RPL9 cleaves PubMed
small ribosomal subunit protein eS17 RPS17 cleaves PubMed
small ribosomal subunit protein eS19 isoform 1 RPS19 cleaves PubMed
small ribosomal subunit protein uS12 RPS23 cleaves PubMed
small ribosomal subunit protein eS24 isoform c RPS24 cleaves PubMed
small ribosomal subunit protein eS1 isoform 1 RPS3A cleaves PubMed
small ribosomal subunit protein eS7 RPS7 cleaves PubMed
ribosome biogenesis regulatory protein homolog RRS1 cleaves PubMed
serine--tRNA ligase, cytoplasmic isoform a SARS1 interacts with PubMed
SART1 cleaves PubMed
plasma protease C1 inhibitor precursor SERPING1 cleaves PubMed
splicing factor 3A subunit 3 isoform 1 SF3A3 interacts with PubMed
SF3B2 cleaves PubMed
ADP/ATP translocase 1 SLC25A4 cleaves PubMed
antileukoproteinase precursor SLPI enhanced by PubMed
SLPI inhibited by PubMed
probable global transcription activator SNF2L2 isoform a SMARCA2 cleaves PubMed
telomerase-binding protein EST1A isoform 1 SMG6 interacts with PubMed
staphylococcal nuclease domain-containing protein 1 SND1 cleaves PubMed
SNW domain-containing protein 1 isoform 2 SNW1 cleaves PubMed
spindlin-2A SPIN2A cleaves PubMed
spectrin alpha chain, erythrocytic 1 SPTA1 cleaves PubMed
SPTA1 cleaves PubMed
SPTAN1 cleaves PubMed
spectrin beta chain, erythrocytic isoform b SPTB cleaves PubMed
spectrin beta chain, non-erythrocytic 1 isoform 1 SPTBN1 cleaves PubMed
spectrin beta chain, non-erythrocytic 2 SPTBN2 cleaves PubMed
spectrin beta chain, non-erythrocytic 4 isoform sigma1 SPTBN4 cleaves PubMed
spectrin beta chain, non-erythrocytic 5 SPTBN5 cleaves PubMed
SRP72 cleaves PubMed
serine/arginine repetitive matrix protein 1 isoform 2 SRRM1 cleaves PubMed
lupus La protein SSB cleaves PubMed
serine/threonine-protein kinase 38 STK38 cleaves PubMed
serine/threonine-protein kinase 38-like STK38L cleaves PubMed
switch-associated protein 70 isoform 1 SWAP70 cleaves PubMed
THRAP3 cleaves PubMed
mitochondrial import inner membrane translocase subunit Tim10 TIMM10 cleaves PubMed
transketolase isoform 1 TKT cleaves PubMed
talin-1 TLN1 cleaves PubMed
talin-2 TLN2 cleaves PubMed
troponin C, slow skeletal and cardiac muscles TNNC1 cleaves PubMed
troponin C, skeletal muscle TNNC2 cleaves PubMed
mitochondrial import receptor subunit TOM22 homolog TOMM22 interacts with PubMed
TOMM22 cleaves PubMed
tropomyosin alpha-1 chain isoform Tpm1.5cy TPM1 degrades PubMed
TPM1 cleaves PubMed
tropomyosin beta chain isoform Tpm2.2st TPM2 degrades PubMed
tropomyosin alpha-3 chain isoform Tpm3.12st TPM3 degrades PubMed
zinc finger transcription factor Trps1 isoform 1 TRPS1 interacts with PubMed
TUBA1B cleaves PubMed
elongation factor Tu, mitochondrial isoform 1 precursor TUFM cleaves PubMed
UPF1 cleaves PubMed
VBP1 interacts with PubMed
voltage-dependent anion-selective channel protein 1 isoform 1 VDAC1 cleaves PubMed
VDAC1 interacts with PubMed
VIM cleaves PubMed
VIM cleaves PubMed
VIM cleaves PubMed
VIM degrades PubMed
VIM cleaves PubMed
actin nucleation-promoting factor WAS WAS cleaves PubMed
YWHAE cleaves PubMed
YY1 cleaves PubMed
zinc finger CCCH-type antiviral protein 1 isoform 1 ZC3HAV1 cleaves PubMed
CAAX prenyl protease 1 homolog ZMPSTE24 interacts with PubMed
zinc finger protein 202 isoform 1 ZNF202 cleaves PubMed
zinc finger protein 292 isoform 1 ZNF292 cleaves PubMed
E3 ubiquitin-protein ligase ZNF598 isoform 1 ZNF598 cleaves PubMed
protein ZNRD2 isoform 1 ZNRD2 interacts with PubMed
ACTA1 interacts with PubMed
ACTA1 co-localizes with PubMed
ACTA2 interacts with PubMed
ACTA2 co-localizes with PubMed
ACTB co-localizes with PubMed
ACTB binds PubMed
ACTC1 interacts with PubMed
ACTC1 co-localizes with PubMed
ACTG1 interacts with PubMed
ACTG1 co-localizes with PubMed
ACTG2 interacts with PubMed
ACTG2 co-localizes with PubMed
double-stranded RNA-specific adenosine deaminase isoform a ADAR inhibited by PubMed
A-kinase anchor protein 1, mitochondrial precursor AKAP1 binds PubMed
AKAP8L associates with PubMed
APOBEC3F inhibited by PubMed
APOBEC3F interacts with PubMed
APOBEC3G binds PubMed
APOBEC3G interacts with PubMed
APOBEC3G inhibited by PubMed
APOBEC3G inhibited by PubMed
APOBEC3G inhibited by PubMed
APOBEC3G binds PubMed
APOBEC3G interacts with PubMed
APOBEC3G activates PubMed
APOBEC3G interacts with PubMed
ATG16L1 interacts with PubMed
ATG16L2 interacts with PubMed
caveolin-1 isoform alpha CAV1 inhibited by PubMed
cyclin-T1 isoform b CCNT1 inhibited by PubMed
cyclin-dependent kinase inhibitor 2A isoform p16INK4a CDKN2A inhibited by PubMed
cyclic GMP-AMP synthase isoform 1 CGAS cooperates with PubMed
CLTA incorporates PubMed
CLTB incorporates PubMed
CLTC incorporates PubMed
cleavage and polyadenylation specificity factor subunit 6 isoform 1 CPSF6 inhibited by PubMed
granulocyte-macrophage colony-stimulating factor precursor CSF2 interacts with PubMed
CSNK2A1 phosphorylated by PubMed
CSNK2A1 stimulated by PubMed
CSNK2A2 phosphorylated by PubMed
CSNK2A2 stimulated by PubMed
CSNK2B phosphorylated by PubMed
CSNK2B stimulated by PubMed
CXCL8 interacts with PubMed
DHX9 regulated by PubMed
cytoplasmic dynein 1 heavy chain 1 DYNC1H1 regulated by PubMed
cytoplasmic dynein 2 heavy chain 1 isoform 1 DYNC2H1 regulated by PubMed
DYNLL1 interacts with PubMed
DYNLL1 interacts with PubMed
ELAVL1 interacts with PubMed
ELAVL1 interacts with PubMed
ELAVL1 interacts with PubMed
fragile X messenger ribonucleoprotein 1 isoform ISO1 FMR1 associates with PubMed
GEMIN2 stimulated by PubMed
GRB2 interacts with PubMed
hepatitis A virus cellular receptor 1 isoform a precursor HAVCR1 inhibited by PubMed
hepatitis A virus cellular receptor 2 precursor HAVCR2 inhibited by PubMed
HAVCR2 inhibited by PubMed
histone deacetylase 4 isoform 2 HDAC4 regulated by PubMed
HDGFL2 interacts with PubMed
HSPD1 interacts with PubMed
intercellular adhesion molecule 1 precursor ICAM1 interacts with PubMed
interferon alpha-1/13 precursor IFNA1 inhibited by PubMed
IFNA1 inhibited by PubMed
interferon alpha-10 precursor IFNA10 inhibited by PubMed
IFNA10 inhibited by PubMed
IFNA13 inhibited by PubMed
IFNA13 inhibited by PubMed
interferon alpha-14 precursor IFNA14 inhibited by PubMed
IFNA14 inhibited by PubMed
interferon alpha-16 precursor IFNA16 inhibited by PubMed
IFNA16 inhibited by PubMed
interferon alpha-17 precursor IFNA17 inhibited by PubMed
IFNA17 inhibited by PubMed
interferon alpha-2 precursor IFNA2 inhibited by PubMed
IFNA2 inhibited by PubMed
interferon alpha-21 precursor IFNA21 inhibited by PubMed
IFNA21 inhibited by PubMed
interferon alpha-4 precursor IFNA4 inhibited by PubMed
IFNA4 inhibited by PubMed
interferon alpha-5 precursor IFNA5 inhibited by PubMed
IFNA5 inhibited by PubMed
interferon alpha-6 precursor IFNA6 inhibited by PubMed
IFNA6 inhibited by PubMed
interferon alpha-7 precursor IFNA7 inhibited by PubMed
IFNA7 inhibited by PubMed
interferon alpha-8 precursor IFNA8 inhibited by PubMed
IFNA8 inhibited by PubMed
interferon beta precursor IFNB1 upregulates PubMed
interferon gamma precursor IFNG degraded by PubMed
IL10 inhibited by PubMed
interleukin-12 subunit alpha isoform 1 precursor IL12A downregulated by PubMed
interleukin-12 subunit beta precursor IL12B downregulated by PubMed
interleukin-13 isoform 1 precursor IL13 inhibited by PubMed
IL1B interacts with PubMed
IPO7 interacts with PubMed
IPO7 imported by PubMed
interferon regulatory factor 3 isoform 1 IRF3 activates PubMed
KARS1 interacts with PubMed
lactoperoxidase isoform 1 preproprotein LPO inhibited by PubMed
lactotransferrin isoform 1 preproprotein LTF inhibited by PubMed
dual specificity mitogen-activated protein kinase kinase 1 isoform 1 MAP2K1 interacts with PubMed
MAPK1 interacts with PubMed
mitogen-activated protein kinase 12 isoform 1 MAPK12 interacts with PubMed
mitogen-activated protein kinase 3 isoform 1 MAPK3 interacts with PubMed
NCL fractionates with PubMed
nuclear factor of activated T-cells, cytoplasmic 1 isoform B NFATC1 enhanced by PubMed
nuclear factor of activated T-cells, cytoplasmic 2 isoform B NFATC2 enhanced by PubMed
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 NHERF1 interacts with PubMed
NLRP3 interacts with PubMed
nucleoside diphosphate kinase A isoform b NME1 complexes with PubMed
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform 1 PIK3C2A phosphorylated by PubMed
PPIA enhanced by PubMed
PRKCA phosphorylated by PubMed
protein kinase C beta type isoform 1 PRKCB phosphorylated by PubMed
PRKCD phosphorylated by PubMed
PRKCE phosphorylated by PubMed
PRKCG phosphorylated by PubMed
PRKCH phosphorylated by PubMed
PRKCI phosphorylated by PubMed
PRKCQ phosphorylated by PubMed
PRKCZ phosphorylated by PubMed
PSMB8 degraded by PubMed
protein-tyrosine kinase 2-beta isoform a PTK2B interacts with PubMed
PTK2B interacts with PubMed
ras-related protein Rab-11A isoform 1 RAB11A interacts with PubMed
ras-related protein Rab-7a RAB7A interacts with PubMed
replication protein A 70 kDa DNA-binding subunit isoform 1 RPA1 inhibited by PubMed
replication protein A 32 kDa subunit isoform 1 RPA2 inhibited by PubMed
replication protein A 14 kDa subunit RPA3 inhibited by PubMed
replication protein A 30 kDa subunit RPA4 inhibited by PubMed
deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform 1 SAMHD1 regulated by PubMed
SAMHD1 regulated by PubMed
SAMHD1 regulated by PubMed
proto-oncogene tyrosine-protein kinase Src SRC interacts with PubMed
syntaxin-binding protein 2 isoform a STXBP2 regulated by PubMed
trimethylguanosine synthase isoform 1 TGS1 enhances PubMed
T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor TIMD4 inhibited by PubMed
toll-like receptor 7 precursor TLR7 inhibited by PubMed
DNA topoisomerase 1 TOP1 enhanced by PubMed
TOP1 enhanced by PubMed
DNA topoisomerase 2-alpha TOP2A co-localizes with PubMed
DNA topoisomerase 2-beta isoform 2 TOP2B co-localizes with PubMed
TP53 interacts with PubMed
tumor susceptibility gene 101 protein TSG101 inhibited by PubMed
EEF1A1 interacts with PubMed
EEF1A1 interacts with PubMed
EEF1G interacts with PubMed
ICAM1 interacts with PubMed

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Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Preferred Names
Gag-Pol
Names
Gag-Pol polyprotein
aspartic peptidase
p66 subunit
integrase
Gag-Pol Transframe peptide
Pol
reverse transcriptase p51 subunit
NP_057849.4
  • Pr160

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001802.1 Reference assembly

    Range
    336..4642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_057849.4 Gag-Pol [Human immunodeficiency virus 1]

    See identical proteins and their annotated locations for NP_057849.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O09777, P04585, P0C6F2, Q9WJC5
    Conserved Domains (12) summary
    smart00343
    Location:391 → 406
    ZnF_C2HC; zinc finger
    cd01645
    Location:605 → 821
    RT_Rtv; RT_Rtv: Reverse transcriptases (RTs) from retroviruses (Rtvs). RTs catalyze the conversion of single-stranded RNA into double-stranded viral DNA for integration into host chromosomes. Proteins in this subfamily contain long terminal repeats (LTRs) and ...
    pfam00540
    Location:2 → 132
    Gag_p17; gag gene protein p17 (matrix protein)
    pfam00075
    Location:1024 → 1144
    RNase_H; RNase H
    pfam00077
    Location:495 → 586
    RVP; Retroviral aspartyl protease
    pfam00078
    Location:650 → 821
    RVT_1; Reverse transcriptase (RNA-dependent DNA polymerase)
    pfam00552
    Location:1368 → 1415
    IN_DBD_C; Integrase DNA binding domain
    pfam00607
    Location:149 → 363
    Gag_p24; gag gene protein p24 (core nucleocapsid protein)
    pfam00665
    Location:1205 → 1306
    rve; Integrase core domain
    pfam02022
    Location:1155 → 1192
    Integrase_Zn; Integrase Zinc binding domain
    pfam06815
    Location:905 → 1006
    RVT_connect; Reverse transcriptase connection domain
    pfam06817
    Location:830 → 883
    RVT_thumb; Reverse transcriptase thumb domain

  2. NP_705926.1 aspartic peptidase

    UniProtKB/TrEMBL
    A0A1D8B9K4, C8AZH8, C8B397, C8B467, C8BBQ5, E9JDN4, O92103, O92139, Q5RZ08, Q5RZ09, Q72874, Q8Q3H0, Q903J0, Q9J2P7, Q9Q288, Q9Q2G8
    Conserved Domains (1) summary
    pfam00077
    Location:7 → 98
    RVP; Retroviral aspartyl protease

  3. NP_705927.1 p66 subunit

    UniProtKB/TrEMBL
    H9BTT0, H9BTT1
    Conserved Domains (4) summary
    cd01645
    Location:18 → 234
    RT_Rtv; Reverse transcriptases (RTs) from retroviruses (Rtvs). RTs catalyze the conversion of single-stranded RNA into double-stranded viral DNA for integration into host chromosomes. Proteins in this subfamily contain long terminal repeats (LTRs) and are ...
    pfam00075
    Location:437 → 557
    RNase_H; RNase H
    pfam06815
    Location:318 → 419
    RVT_connect; Reverse transcriptase connection domain
    pfam06817
    Location:241 → 296
    RVT_thumb; Reverse transcriptase thumb domain

  4. NP_705928.1 integrase

    UniProtKB/TrEMBL
    A0A0U2T7G9, A0A0U2V1G2, A0A0U5B5J2, A0A3T0QI36, A0A8F3DM09
    Conserved Domains (3) summary
    pfam00552
    Location:221 → 268
    IN_DBD_C; Integrase DNA binding domain
    pfam00665
    Location:58 → 159
    rve; Integrase core domain
    pfam02022
    Location:8 → 45
    Integrase_Zn; Integrase Zinc binding domain

  5. NP_787043.1 Gag-Pol Transframe peptide

    UniProtKB/TrEMBL
    A5YJG5, A5YJJ3

  6. NP_789740.1 Pol

    UniProtKB/TrEMBL
    A0A6G6D3R8
    Conserved Domains (9) summary
    cd01645
    Location:165 → 381
    RT_Rtv; RT_Rtv: Reverse transcriptases (RTs) from retroviruses (Rtvs). RTs catalyze the conversion of single-stranded RNA into double-stranded viral DNA for integration into host chromosomes. Proteins in this subfamily contain long terminal repeats (LTRs) and ...
    pfam00075
    Location:584 → 704
    RNase_H; RNase H
    pfam00077
    Location:55 → 146
    RVP; Retroviral aspartyl protease
    pfam00078
    Location:210 → 381
    RVT_1; Reverse transcriptase (RNA-dependent DNA polymerase)
    pfam00552
    Location:928 → 975
    IN_DBD_C; Integrase DNA binding domain
    pfam00665
    Location:765 → 866
    rve; Integrase core domain
    pfam02022
    Location:715 → 752
    Integrase_Zn; Integrase Zinc binding domain
    pfam06815
    Location:465 → 566
    RVT_connect; Reverse transcriptase connection domain
    pfam06817
    Location:390 → 443
    RVT_thumb; Reverse transcriptase thumb domain

  7. NP_789739.1 reverse transcriptase p51 subunit

    Conserved Domains (3) summary
    pfam06815
    Location:318 → 419
    RVT_connect; Reverse transcriptase connection domain
    pfam06817
    Location:241 → 296
    RVT_thumb; Reverse transcriptase thumb domain
    cl02808
    Location:18 → 234
    RT_like; Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, retroviruses, group ...
Nucleotide Protein
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