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TTC24 tetratricopeptide repeat domain 24 [ Homo sapiens (human) ]

Gene ID: 164118, updated on 17-Sep-2024

Summary

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Official Symbol
TTC24provided by HGNC
Official Full Name
tetratricopeptide repeat domain 24provided by HGNC
Primary source
HGNC:HGNC:32348
See related
Ensembl:ENSG00000187862 AllianceGenome:HGNC:32348
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in lymph node (RPKM 3.0), spleen (RPKM 1.9) and 3 other tissues See more
Orthologs
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Genomic context

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See TTC24 in Genome Data Viewer
Location:
1q22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (156579723..156587719)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (155716091..155724195)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (156549515..156557511)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156432711-156433660 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156445026-156445638 Neighboring gene myocyte enhancer factor 2D Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1863 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1864 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1865 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1866 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1867 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156466171-156466671 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1428 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156471045-156471824 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1429 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1868 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:156474933-156475335 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1870 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1869 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:156483472-156483678 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1430 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr1:156495835-156496406 Neighboring gene small nucleolar RNA U13 Neighboring gene IQ motif containing GTPase activating protein 3 Neighboring gene NANOG hESC enhancer GRCh37_chr1:156508711-156509291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1871 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1872 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1873 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156554411-156554912 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:156554913-156555412 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:156561722-156562568 Neighboring gene G-patch domain containing 4 (gene/pseudogene) Neighboring gene NAD(P)HX epimerase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
  2. In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker. Gao H, et al. Anal Chem, 2022 May 31. PMID 35575683

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • FLJ20249

General protein information

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Preferred Names
tetratricopeptide repeat protein 24
Names
TPR repeat protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105669.4 → NP_001099139.2  tetratricopeptide repeat protein 24

    See identical proteins and their annotated locations for NP_001099139.2

    Status: VALIDATED

    Source sequence(s)
    AL365181
    Consensus CDS
    CCDS53379.1
    UniProtKB/Swiss-Prot
    A2A3L6, Q5T3H7
    Related
    ENSP00000357219.3, ENST00000368236.8
    Conserved Domains (5) summary
    smart00028
    Location:273 → 302
    TPR; Tetratricopeptide repeats
    sd00006
    Location:273 → 301
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:353 → 380
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:121 → 180
    TPR_11; TPR repeat
    pfam13424
    Location:271 → 345
    TPR_12; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    156579723..156587719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047447969.1 → XP_047303925.1  tetratricopeptide repeat protein 24 isoform X3

  2. XM_011509253.3 → XP_011507555.2  tetratricopeptide repeat protein 24 isoform X1

  3. XM_011509255.3 → XP_011507557.2  tetratricopeptide repeat protein 24 isoform X4

  4. XM_047447973.1 → XP_047303929.1  tetratricopeptide repeat protein 24 isoform X6

  5. XM_011509254.3 → XP_011507556.2  tetratricopeptide repeat protein 24 isoform X2

  6. XM_047447971.1 → XP_047303927.1  tetratricopeptide repeat protein 24 isoform X5

  7. XM_047447977.1 → XP_047303933.1  tetratricopeptide repeat protein 24 isoform X8

  8. XM_047447975.1 → XP_047303931.1  tetratricopeptide repeat protein 24 isoform X7

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791758.1 Reference GRCh38.p14 PATCHES

    Range
    138280..146384
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332835.1 → XP_054188810.1  tetratricopeptide repeat protein 24 isoform X3

  2. XM_054332840.1 → XP_054188815.1  tetratricopeptide repeat protein 24 isoform X8

  3. XM_054332833.1 → XP_054188808.1  tetratricopeptide repeat protein 24 isoform X1

  4. XM_054332836.1 → XP_054188811.1  tetratricopeptide repeat protein 24 isoform X4

  5. XM_054332838.1 → XP_054188813.1  tetratricopeptide repeat protein 24 isoform X6

  6. XM_054332834.1 → XP_054188809.1  tetratricopeptide repeat protein 24 isoform X2

  7. XM_054332837.1 → XP_054188812.1  tetratricopeptide repeat protein 24 isoform X5

  8. XM_054332839.1 → XP_054188814.1  tetratricopeptide repeat protein 24 isoform X7

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    155716091..155724195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054334786.1 → XP_054190761.1  tetratricopeptide repeat protein 24 isoform X3

  2. XM_054334791.1 → XP_054190766.1  tetratricopeptide repeat protein 24 isoform X8

  3. XM_054334784.1 → XP_054190759.1  tetratricopeptide repeat protein 24 isoform X1

  4. XM_054334787.1 → XP_054190762.1  tetratricopeptide repeat protein 24 isoform X4

  5. XM_054334789.1 → XP_054190764.1  tetratricopeptide repeat protein 24 isoform X6

  6. XM_054334785.1 → XP_054190760.1  tetratricopeptide repeat protein 24 isoform X2

  7. XM_054334788.1 → XP_054190763.1  tetratricopeptide repeat protein 24 isoform X5

  8. XM_054334790.1 → XP_054190765.1  tetratricopeptide repeat protein 24 isoform X7

RNA

  1. XR_008485940.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2A3L6.1 GenPept UniProtKB/Swiss-Prot:A2A3L6

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