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Cyp4f13 cytochrome P450, family 4, subfamily f, polypeptide 13 [ Mus musculus (house mouse) ]

Gene ID: 170716, updated on 28-Oct-2024

Summary

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Official Symbol
Cyp4f13provided by MGI
Official Full Name
cytochrome P450, family 4, subfamily f, polypeptide 13provided by MGI
Primary source
MGI:MGI:2158641
See related
Ensembl:ENSMUSG00000024055 AllianceGenome:MGI:2158641
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cypf13; 0610030I10Rik
Summary
Predicted to enable monooxygenase activity. Predicted to be involved in fatty acid metabolic process. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human CYP4F3 (cytochrome P450 family 4 subfamily F member 3). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in duodenum adult (RPKM 29.8), liver adult (RPKM 28.4) and 27 other tissues See more
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Genomic context

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See Cyp4f13 in Genome Data Viewer
Location:
17 B1; 17 17.98 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33143662..33166389, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32924688..32947415, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42397 Neighboring gene zinc finger protein 870 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33028261-33028519 Neighboring gene STARR-seq mESC enhancer starr_42399 Neighboring gene STARR-seq mESC enhancer starr_42400 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 14 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33084248-33084483 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 41 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7516 Neighboring gene zinc finger protein 472

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Confirmation of Ath26 locus on chromosome 17 and identification of Cyp4f13 as an atherosclerosis modifying gene. Han J, et al. Atherosclerosis, 2019 Jul. PMID 31102955, Free PMC Article
  2. Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues. Choudhary D, et al. Arch Biochem Biophys, 2003 Jun 1. PMID 12745259
  3. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  4. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 20-aldehyde-leukotriene B4 20-monooxygenase activity ISO
Inferred from Sequence Orthology
more info
  
enables 20-hydroxy-leukotriene B4 omega oxidase activity ISO
Inferred from Sequence Orthology
more info
  
enables leukotriene-B4 20-monooxygenase activity ISO
Inferred from Sequence Orthology
more info
  
enables long-chain fatty acid omega-1 hydroxylase activity ISO
Inferred from Sequence Orthology
more info
  
enables long-chain fatty acid omega-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
  
enables very long-chain fatty acid omega-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in fatty acid omega-oxidation ISO
Inferred from Sequence Orthology
more info
  
involved_in leukotriene B4 catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in leukotriene metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in lipoxin A4 metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in lipoxin B4 metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in omega-hydroxylase P450 pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
cytochrome P450, family 4, subfamily f, polypeptide 13
Names
P450 CYP4F13
cytochrome P450 CYP4F13
cytochrome P450,subfamily IVF, polypeptide 13
leukotriene B4 omega hydroxylase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417675.1 → NP_001404604.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT033772

  2. NM_001417676.1 → NP_001404605.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT033772

  3. NM_001417677.1 → NP_001404606.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT033772

  4. NM_001417678.1 → NP_001404607.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT033772

  5. NM_130882.2 → NP_570952.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform 1

    See identical proteins and their annotated locations for NP_570952.1

    Status: VALIDATED

    Source sequence(s)
    CT033772
    Consensus CDS
    CCDS28622.1
    UniProtKB/TrEMBL
    Q99KY6, Q99N19
    Related
    ENSMUSP00000074733.7, ENSMUST00000075253.13
    Conserved Domains (1) summary
    pfam00067
    Location:52 → 513
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    33143662..33166389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523736.4 → XP_006523799.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform X3

    See identical proteins and their annotated locations for XP_006523799.1

    UniProtKB/TrEMBL
    B8JK07
    Conserved Domains (1) summary
    pfam00067
    Location:45 → 372
    p450; Cytochrome P450

  2. XM_006523737.4 → XP_006523800.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform X3

    See identical proteins and their annotated locations for XP_006523800.1

    UniProtKB/TrEMBL
    B8JK07
    Conserved Domains (1) summary
    pfam00067
    Location:45 → 372
    p450; Cytochrome P450

  3. XM_006523738.3 → XP_006523801.1  cytochrome P450, family 4, subfamily f, polypeptide 13 isoform X4

    Conserved Domains (1) summary
    cl12078
    Location:52 → 374
    p450; Cytochrome P450
Nucleotide Protein Strain
Heading Accession and Version

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