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Igsf6 immunoglobulin superfamily, member 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 171064, updated on 17-Aug-2024

Summary

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Official Symbol
Igsf6provided by RGD
Official Full Name
immunoglobulin superfamily, member 6provided by RGD
Primary source
RGD:620663
See related
EnsemblRapid:ENSRNOG00000017277 AllianceGenome:RGD:620663
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
DORA
Summary
Predicted to be integral component of membrane. Orthologous to human IGSF6 (immunoglobulin superfamily member 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 135.8), Lung (RPKM 107.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Igsf6 in Genome Data Viewer
Location:
1q36
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (185041462..185051956, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (175610167..175620662, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (190997029..191007503, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene major facilitator superfamily domain containing 13B Neighboring gene U6 spliceosomal RNA Neighboring gene methyltransferase 9, His-X-His N1(pi)-histidine Neighboring gene otoancorin Neighboring gene uncharacterized LOC108349630

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamily. Bates EE, et al. Mol Immunol, 1998 Jun. PMID 9809579

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
immunoglobulin superfamily member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133542.3 → NP_598226.2  immunoglobulin superfamily member 6 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    Q9Z0K5
    UniProtKB/TrEMBL
    A6I8U1
    Related
    ENSRNOP00000023262.3, ENSRNOT00000023262.4
    Conserved Domains (2) summary
    cd00096
    Location:45 → 54
    Ig; Ig strand B [structural motif]
    cl11960
    Location:34 → 142
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    185041462..185051956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Z0K5.1 GenPept UniProtKB/Swiss-Prot:Q9Z0K5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
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