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Glyatl2 glycine-N-acyltransferase-like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 171179, updated on 2-Nov-2024

Summary

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Official Symbol
Glyatl2provided by RGD
Official Full Name
glycine-N-acyltransferase-like 2provided by RGD
Primary source
RGD:621231
See related
EnsemblRapid:ENSRNOG00000012387 AllianceGenome:RGD:621231
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
HP33; Keg1
Summary
Predicted to enable N-acyltransferase activity. Located in centrosome. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 741.8) and Liver (RPKM 562.8) See more
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Genomic context

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See Glyatl2 in Genome Data Viewer
Location:
1q43
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (219232154..219265142)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (209807488..209840480)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (229519586..229552573)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily B member 95 like 1 Neighboring gene olfactory receptor family 5 subfamily B member 95 Neighboring gene ciliary neurotrophic factor Neighboring gene zinc finger protein 91 Neighboring gene leupaxin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. HP33: hepatocellular carcinoma-enriched 33-kDa protein with similarity to mitochondrial N-acyltransferase but localized in a microtubule-dependent manner at the centrosome. Nakadai T, et al. J Cell Sci, 1999 May. PMID 10194414
  2. Structure of rat gamma-tubulin and its binding to HP33. Nakadai T, et al. DNA Res, 1999 Jun 30. PMID 10470852
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gamma-tubulin binding NAS
Non-traceable Author Statement
more info
 PubMed 
enables glycine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in centrosome NAS
Non-traceable Author Statement
more info
 PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glycine N-acyltransferase-like protein Keg1
Names
Acyl-CoA:glycine N-acyltransferase protein Keg1
glycine N-acyltransferase protein Keg1
hepatocellular carcinoma-enriched protein of 33 kDa
kidney expressed gene 1
kidney-expressed gene 1 protein
NP_599157.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134330.2 → NP_599157.2  glycine N-acyltransferase-like protein Keg1

    See identical proteins and their annotated locations for NP_599157.2

    Status: PROVISIONAL

    Source sequence(s)
    BC078701
    UniProtKB/Swiss-Prot
    Q68G42, Q9Z2Y0
    UniProtKB/TrEMBL
    A0A8I6A4V2, A6I0E6
    Related
    ENSRNOP00000016593.4, ENSRNOT00000016593.8
    Conserved Domains (2) summary
    pfam08444
    Location:206 → 294
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1 → 205
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    219232154..219265142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9Z2Y0.2 GenPept UniProtKB/Swiss-Prot:Q9Z2Y0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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