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F56C11.3 Sulfhydryl oxidase [ Caenorhabditis elegans ]

Gene ID: 171611, updated on 2-Nov-2024

Summary

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Official Symbol
F56C11.3
Official Full Name
Sulfhydryl oxidase
Primary source
WormBase:WBGene00018955
Locus tag
CELE_F56C11.3
See related
AllianceGenome:WB:WBGene00018955
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable flavin adenine dinucleotide binding activity and flavin-dependent sulfhydryl oxidase activity. Predicted to be active in mitochondrion. Is expressed in body wall musculature; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Orthologous to human GFER (growth factor, augmenter of liver regeneration). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F56C11.3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (182068..182772, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Carboxylic ester hydrolase Neighboring gene ncRNA Neighboring gene MARVEL domain-containing protein Neighboring gene tRNA Neighboring gene Serine/threonine-protein kinase ATM Neighboring gene Carbohydrate sulfotransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables flavin-dependent sulfhydryl oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables flavin-dependent sulfhydryl oxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables thiol oxidase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Sulfhydryl oxidase
NP_490690.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    182068..182772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058289.4 → NP_490690.1  Sulfhydryl oxidase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490690.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44975
    Conserved Domains (1) summary
    pfam04777
    Location:60 → 148
    Evr1_Alr; Erv1 / Alr family
Nucleotide Protein
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